Results 41 to 50 of about 3,267,627 (304)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Multi‐Decadal Skill Variability in Predicting the Spatial Patterns of ENSO Events
Geophysical Research LettersSeasonal hindcasts have previously been demonstrated to show multi‐decadal variability in skill across the twentieth century in indices describing El‐Niño Southern Oscillation (ENSO), which drives global seasonal predictability.
M. J. Wright +2 more
doaj +1 more source
Optimal spatial scales for seasonal forecasts over Africa
Environmental Research Letters, 2020 The availability of seasonal weather forecast information in Africa has potential to provide advanced early warning of rainfall variability, informing preparedness actions to minimise adverse impacts.
Matthew Young +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Journal of Transport and Land Use, 2012 As a result of public investment, lower freight transport costs tend to translate into lower local price indices and are associated with equilibria characterized by higher capital intensity, output and consumption.
Ioannis Tikoudis +2 more
doaj +1 more source
Influence of proxy data uncertainty on data assimilation for the past climate [PDF]
Climate of the Past, 2016 Data assimilation (DA) is an emerging topic in palaeoclimatology and one of the key challenges in this field. Assimilating proxy-based continental mean temperature reconstructions into the MPI-ESM model showed a lack of information propagation to small ...
A. Matsikaris, M. Widmann, J. Jungclaus
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Priming as a means of preventing skill failure under pressure [PDF]
, 2010 Copyright @ 2010 Human KineticsThe present study examined the effectiveness of a priming paradigm in alleviating skill failure under stress. The priming intervention took the form of a scrambled sentence task.
Ashford, K, Jackson, RC
core +5 more sources
SensorsIn sports training, personalized skill assessment and feedback are crucial for athletes to master complex movements and improve performance. However, existing research on skill transfer predominantly focuses on skill evaluation through video analysis ...
Tatsuki Seino +4 more
doaj +1 more source
Improving cognitive mapping by training for people with a poor sense of direction
Cognitive Research, 2020 The skill of spatial learning and orientation is fundamental in humans and differs widely among individuals. Despite its importance, however, the malleability of this skill through practice has scarcely been studied empirically, in contrast to ...
Toru Ishikawa, Yiren Zhou
doaj +1 more source