Results 71 to 80 of about 1,471,906 (260)

Spatial Wavelet Statistics of SAR Backscatter for Characterizing Degraded Forest: A Case Study From Cameroon

open access: yesIEEE Journal of Selected Topics in Applied Earth Observations and Remote Sensing, 2015
Forest degradation is an important issue in global environmental studies, albeit not yet well defined in quantitative terms. The present work addresses the problem, by starting with the assumption that forest spatial structure can provide an indication ...
Elsa C. De Grandi   +3 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Score, Pseudo-Score and Residual Diagnostics for Spatial Point Process Models

open access: yes, 2011
We develop new tools for formal inference and informal model validation in the analysis of spatial point pattern data. The score test is generalized to a "pseudo-score" test derived from Besag's pseudo-likelihood, and to a class of diagnostics based on ...
Baddeley, Adrian   +2 more
core   +1 more source

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

open access: yesMolecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg   +43 more
wiley   +1 more source

Spatial and Temporal Effects of Built Environment on Urban Air Temperature in Seoul City, Korea: An Application of Spatial Regression Models

open access: yesJournal of Asian Architecture and Building Engineering, 2017
In this study we examined the relationships between the built environment and urban air temperature in Seoul city, Korea. We developed multivariate regression models that address the relationship between built environment characteristics and the ambient ...
Sugie Lee, Jaehyun Ha, Hyemin Cho
doaj   +1 more source

An Overview of Spatial Econometrics

open access: yes, 2016
This paper offers an expository overview of the field of spatial econometrics. It first justifies the necessity of special statistical procedures for the analysis of spatial data and then proceeds to describe the fundamentals of these procedures.
Tybl, Alexander J.
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Using Satellite Thermal-Based Evapotranspiration Time Series for Defining Management Zones and Spatial Association to Local Attributes in a Vineyard

open access: yesRemote Sensing, 2020
A well-planned irrigation management strategy is crucial for successful wine grape production and is highly dependent on accurate assessments of water stress.
Noa Ohana-Levi   +8 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

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