Results 141 to 150 of about 7,213,322 (346)

Long-term spatial-temporal trends and variability of rainfall over Eastern and Southern Africa

Theoretical and Applied Climatology, 2018
This study investigates the spatial-temporal trends and variability of rainfall within East and South Africa (ESA) region. The newly available Climate Hazards group Infrared Precipitation with Stations (CHIRPS-v2) gridded data spanning 37 years (1981 to ...
F. Muthoni, V. Odongo, J. Ochieng, E. Mugalavai, S. Mourice, Irmgard Hoesche-Zeledon, M. Mwila, M. Bekunda   +7 more
semanticscholar   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Mapping fertility rates at national, sub-national, and local levels in Ethiopia between 2000 and 2019

Frontiers in Public Health
BackgroundFertility rates are key indicators of population health and demographic change, influencing economic development, healthcare planning, and social policies.
Biruk Beletew Abate, Biruk Beletew Abate, Ashenafi Kibret Sendekie, Ashenafi Kibret Sendekie, Mulat Ayele, Eyob Shitie Lake, Tilahun Wodaynew, Befkad Derese Tilahun, Molla Azmeraw, Tesfaye Engdaw Habtie, Muluemebet Kassa, Melesse Abiye Munie, Dessie Temesgen, Abebe Merchaw, Addis Wondimagegn Alamaw, Alemu Birara Zemariam, Tegene Atamenta Kitaw, Amare Kassaw, Ayelign Mengesha Kassie, Ayelign Mengesha Kassie, Gizachew Yilak, Mulat Awoke Kassa, Gebremeskel Abebe Kibret, Muluken Chanie Agimas, Fasikaw Kebede Bizuneh, Molalign Aligaz Adisu, Bogale Molla Woreta, Kefyalew Addis Alene, Kefyalew Addis Alene   +28 more
doaj   +1 more source

Spatial and temporal changes of spring temperature, thermal growing season and spring phenology in Germany 1951–2015

Meteorologische Zeitschrift, 2018
Climate change has a strong impact on vegetation dynamics and the relationship between temperature changes and shifts in plant development is well known.
Timm Waldau, Frank‑M. Chmielewski
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Trends in spatial domain standards

GIM International, 2015
OTB
Van Oosterom, P.J.M. (author), Lemmen, C.H.J. (author)   +1 more
openaire   +3 more sources

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Temporal Trends and Identification of Suicide Mortality Risk Areas in Brazil (2000–2022): Are We Dealing with an Underestimated Epidemic?

Medicina
Background and Objectives: Suicide is a pressing public health issue globally, including in Brazil, where it ranks among the leading causes of mortality.
Danilo de Gois Souza, Lucas Almeida Andrade, José Augusto Passos Góes, Luís Ricardo Santos de Melo, Matheus Santos Melo, Caíque Jordan Nunes Ribeiro, José Marcos de Jesus Santos, Emerson Lucas Silva Camargo, Álvaro Francisco Lopes de Sousa, Liliane Moretti Carneiro, Regina Claudia da Silva Souza, Márcio Bezerra Santos, Shirley Veronica Melo Almeida Lima, Carla Aparecida Arena Ventura, Allan Dantas dos Santos   +14 more
doaj   +1 more source

Temporal Patterns of the Two-Dimensional Spatial Trends in Summer Temperature and Monsoon Precipitation of Bangladesh

, 2013
Two climate indices, TXx and PRCPTOT, representing the summer maximum temperature and annual total monsoon precipitation, respectively, in Bangladesh were computed. The temperature and precipitation measurements from 34 meteorological stations during the
A. Bhowmik
semanticscholar   +1 more source

Applicability of mitotic figure counting by deep learning: a development and pan‐cancer validation study

FEBS Open Bio, EarlyView.
In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes, Maria X. Isaksen, Frida Julbø, Manohar Pradhan, Andreas Kleppe, Sepp De Raedt, Ole‐Johan Skrede, Turid Torheim, John Arne Nesheim, Hans Martin Mohn, Hanne A. Askautrud, Karolina Cyll, Wanja Kildal, Emma Rewcastle, Melinda Lillesand, Vebjørn Kvikstad, Emiel Janssen, Robert Jones, Odd Terje Brustugun, Bjørn Brennhovd, Erik Skaaheim Haug, Lill‐Tove Rasmussen Busund, Elin Richardsen, Sigve Andersen, Tom Dønnem, Kristina Lindemann, Gunnar Kristensen, Neil A. Shepherd, Marco Novelli, Knut Liestøl, David Kerr, Håvard E. Danielsen, Tarjei S. Hveem   +32 more
wiley   +1 more source