Results 161 to 170 of about 7,213,322 (346)

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

Temporal and Spatial Trends in Benthic Infauna and Potential Drivers, in a Highly Tidal Estuary in Atlantic Canada. [PDF]

Estuaries Coast, 2023
Guerin AJ, Kidd KA, Maltais MJ, Mercer A, Hunt HL.   +4 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Where did people die from cardiovascular disease? Spatial inequalities in cardiovascular mortality in Belgium between 1890 and 2011

Espace populations sociétés
In the early 20th century, mortality due to cardiovascular disease (CVD) was relatively uncommon. Most Western countries only faced a huge increase in cardiovascular deaths during the second part of the 20th century only [Grimmeau et al., 2015].
Lise Bevernaegie, Isabelle Devos, Sylvie Gadeyne   +2 more
doaj   +1 more source

Temporal and Spatial Trends of Adverse Pregnancy and Birth Outcomes in a Sample of Births from a Public Hospital in Chile. [PDF]

J Urban Health, 2023
Blanco E, Ruiz-Rudolph P, Yohannessen K, Ayala S, Quinteros ME, Delgado-Saborit JM, Blazquez CA, Iglesias V, Zapata DA, Bartington SE, Harrison RM, Ossa X.   +11 more
europepmc   +1 more source

Asymptotic Distribution of the OLS Estimator for a Mixed Regressive, Spatial Autoregressive Model [PDF]

We find the asymptotics of the OLS estimator of the parameters $\beta$ and $\rho$ in the spatial autoregressive model with exogenous regressors $Y_n = X_n\beta+\rho W_nY_n+V_n$. Only low-level conditions are imposed.
Mynbaev, Kairat
core   +1 more source

OD Maps for Studying Historical Internal Migration in Ireland [PDF]

, 2012
We study internal migration in Ireland, an aspect of migration that is little-studied. OD Maps have enabled us to characterise aspects of spatial patterns in county to county migration more effectively than with other techniques.
Dykes, J., Kelly, M., Slingsby, A., Wood, J.   +3 more
core  

Decorrelation Times of Photospheric Fields and Flows

, 2012
We use autocorrelation to investigate evolution in flow fields inferred by applying Fourier Local Correlation Tracking (FLCT) to a sequence of high-resolution (0.3 \arcsec), high-cadence ($\simeq 2$ min) line-of-sight magnetograms of NOAA active region ...
Abbett, Abramenko, B. T. Welsch, Berger, Chae, Cheung, DeForest, Fisher, Hagenaar, Hagenaar, Isobe, K. Kusano, K. Muglach, Katsukawa, Longcope, Nesis, Rempel, Scherrer, Schrijver, Schuck, Schuck, Schuck, T. T. Yamamoto, Tan, Tan, Thompson, Verma, Welsch, Welsch, Welsch, Welsch, Welsch, Zuccarello   +32 more
core   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Opioid-related mortality: Dynamic temporal and spatial trends by drug type and demographic subpopulations, Massachusetts, 2005-2021. [PDF]

Drug Alcohol Depend, 2023
Stopka TJ, Larochelle MR, Li X, Bernson D, Li W, Ackerson LK, Bayly R, Dammann O, Bauer C.   +8 more
europepmc   +1 more source