Results 81 to 90 of about 7,213,322 (346)

Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015

open access: yesThe Lancet, 2017
Summary Background Exposure to ambient air pollution increases morbidity and mortality, and is a leading contributor to global disease burden. We explored spatial and temporal trends in mortality and burden of disease attributable to ambient air ...
A. Cohen   +29 more
semanticscholar   +1 more source

Spatial trends in Gauteng [PDF]

open access: yesOccasional Paper, 2021
Richard Ballard   +2 more
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Emerging trends and research frontiers in spatial multicriteria analysis

open access: yesInternational Journal of Geographical Information Science, 2020
A majority of research on Spatial Multicriteria Analysis (SMCA) has been spatially implicit. Typically, SMCA uses conventional (aspatial) multicriteria methods for analysing and solving spatial problems.
J. Malczewski, P. Jankowski
semanticscholar   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Zwischen Ökologisierung des Gewässerschutzes und Kommerzialisierung der Wasserwirtschaft: Neue Handlungsanforderungen an Raumplanung und Regionalpolitik

open access: yesRaumforschung und Raumordnung, 2009
The paper analyses two parallel, but distinct, trends of water management in Germany — the ecological orientation of water protection and the commercialisation of water services — in terms of their relevance for spatial development.
Timothy Moss
doaj   +1 more source

Integrated, adaptive and participatory spatial planning: trends across Europe

open access: yes, 2020
Whether spatial planning systems are equipped to cope with contemporary regional and urban challenges is strongly dependent on their capacity to promote integration between policy sectors, to respond adaptively to changing societal and political ...
V. Nadin   +3 more
semanticscholar   +1 more source

Least squares estimation of nonlinear spatial trends

open access: yesComputational Statistics & Data Analysis, 2010
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Rosa M. Crujeiras, Ingrid Van Keilegom
openaire   +3 more sources

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Temporal and spatial variations in maximum river discharge from a new Russian data set [PDF]

open access: yes, 2007
Floods cause more damage in Russia than any other natural disaster, and future climate model projections suggest that the frequency and magnitude of extreme hydrological events will increase in Russia with climate change.
Lammers, Richard B.   +4 more
core   +3 more sources

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