Results 91 to 100 of about 4,913,721 (332)
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Spatial Variability of Grouting Layer of Shield Tunnel and Its Effect on Ground Settlement
Applied Sciences, 2020 This study aims to investigate the effect of the spatial variability of grouting-layer thickness on ground-surface settlement caused by shield tunneling and to provide a rational prediction method.
Zhongzheng Wang +2 more
doaj +1 more source
A new approach to model the spatial and temporal variability of recharge to karst aquifers [PDF]
Hydrology and Earth System Sciences, 2012 In karst systems, near-surface dissolution of carbonate rock results in a high spatial and temporal variability of groundwater recharge. To adequately represent the dominating recharge processes in hydrological models is still a challenge, especially in ...
A. Hartmann +4 more
doaj +1 more source
Spatial variability of groundwater recharge - II. Factors affecting variability and taking account of it in estimating recharge [PDF]
, 2004 The accompanying paper provided evidence to suggest that spatial variability of groundwater recharge is ‘true’ variability. This paper attempts to determine the major causes of such variability even at small distances, if there appear to be a frequency ...
De Silva, RP
core
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Continental scale variability in ecosystem processes: Models, data, and the role of disturbance [PDF]
, 1997 Management of ecosystems at large regional or continental scales and determination of the vulnerability of ecosystems to large-scale changes in climate or atmospheric chemistry require understanding how ecosystem processes are governed at large spatial ...
Braswell, Rob, Schimel, David S
core +1 more source
Spatial Interdependence and Instrumental Variable Models
Political Science Research and Methods, 2017 Instrumental variable (IV) methods are widely used to address endogeneity concerns in re- search using observational data. Yet, a specific kind of endogeneity – spatial interdependence – is regularly ignored in this research, threatening claims of causal identification.
Betz, Timm +2 more
openaire +3 more sources
Plant and Soil, 2015 AimsDespite multiple studies investigating the environmental controls on CH4 fluxes from arctic tundra ecosystems, the high spatial variability of CH4 emissions is not fully understood.
K. McEwing, J. P. Fisher, D. Zona
semanticscholar +1 more source
Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology
Molecular Oncology, EarlyView.Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts +8 more
wiley +1 more source
Canopy structural modeling using object-oriented image classification and laser scanning [PDF]
, 2008 A terrestrial laser scanning (TLS) experiment was carried out in the EAGLE 2006 campaign to characterize and model the canopy structure of the Speulderbos forest. Semi-variogram analysis was used to describe spatial variability of the surface.
Dost, R. +3 more
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