Results 81 to 90 of about 487,525 (314)
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Computational system for geostatistical analysis
Scientia Agricola, 2004 Geostatistics identifies the spatial structure of variables representing several phenomena and its use is becoming more intense in agricultural activities.
Laurimar Gonçalves Vendrusculo +3 more
doaj
Spatial and temporal variability of idiopathic pulmonary fibrosis cases in Silesian Voivodeship in years 2006–2010 [PDF]
, 2017 Objectives: Idiopathic pulmonary fibrosis (IPF) (J84.1 by the International Statistical Classification of Diseases and Related Health Problems, 10th revision – ICD-10) is a rare disease of unknown cause.
Ewa Niewiadomska +5 more
core +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
How model and input uncertainty impact maize yield simulations in West Africa
Environmental Research Letters, 2015 Crop models are common tools for simulating crop yields and crop production in studies on food security and global change. Various uncertainties however exist, not only in the model design and model parameters, but also and maybe even more important in ...
Katharina Waha +3 more
doaj +1 more source
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Research on the Spatial Variability of Soil Moisture [PDF]
, 2009 China is a country seriously suffering from the lack of water resource, especially the north of China (a dense area) where there are more agricultural production than other places in China. Therefore, some have become most important problems which should be settled down right now for precision agriculture: saving the water of agriculture, optimizing ...
Changli Zhang +3 more
openaire +1 more source
, 2009 The carbon copy of human activities - how long-term land use explains spatial variability of soil organic carbon stocks at multiple ...
Schulp, C.J.E.
core
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source