Results 71 to 80 of about 385,300 (264)
Research on the Spatial Variability of Soil Moisture [PDF]
, 2009 China is a country seriously suffering from the lack of water resource, especially the north of China (a dense area) where there are more agricultural production than other places in China. Therefore, some have become most important problems which should be settled down right now for precision agriculture: saving the water of agriculture, optimizing ...
Changli Zhang +3 more
openaire +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Moravian Geographical Reports, 2017 The variability and geographical patterns of population characteristics are key topics in Human Geography. There are many approaches to exploring and quantitatively measuring this issue.
Netrdová Pavlína, Nosek Vojtěch
doaj +1 more source
International Journal of Technology, 2018 The primary input for hydrological the hydrological model is rainfall. The accurate illustration of rainfall in time and space is important for rainfall-runoff modeling since it impact the hydrological responses.
Evi Anggraheni +4 more
doaj +1 more source
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Spatial variability - So what?
, 2006 Since the landmark papers of Conway and Abrahamson many studies have tried to quantify spatial variability. Many different methods have been used and the studies covered a variety of scales. Accordingly, some results appear contradictory, suggesting that the degree of spatial variation varies widely.
Schweizer, Jürg +3 more
openaire +2 more sources
Molecular Oncology, EarlyView.In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source