Results 61 to 70 of about 4,913,721 (332)
Several studies have shown that Illumina MiSeq high-throughput sequencing can be used to measure the diversity of prokaryotes and fungal communities that provide ecosystem functions in agricultural soils.
Thomas Jeanne +2 more
doaj +1 more source
Temporal and spatial variability in speakers with Parkinson's Disease and Friedreich's Ataxia [PDF]
Speech variability in groups of speakers with Parkinson's disease (PD) and with Friedreich's ataxia was compared with healthy controls. Speakers repeated the same phrase 20 times at one of two rates (fast or habitual).
Anderson, Andrew +2 more
core
Spatial variability in the hyporheic zone refugium of temporary streams [PDF]
A key ecological role hypothesized for the hyporheic zone is as a refugium that promotes survival of benthic invertebrates during adverse conditions in the surface stream.
Reid, I, Stubbington, R, Wood, PJ
core +1 more source
Evaluating spatially variable gene detection methods for spatial transcriptomics data
Abstract Background The identification of genes that vary across spatial domains in tissues and cells is an essential step for spatial transcriptomics data analysis. Given the critical role it serves for downstream data interpretations, various methods for detecting spatially variable genes ...
Carissa Chen +2 more
openaire +3 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Spatial variability of groundwater recharge - I. Is it really variable? [PDF]
The spatial variability of recharge is an important consideration in estimating recharge especially as all methods of estimating it are 'point' estimates and in most places recharge varies in space.
De Silva, RP
core
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Hydrological controls on river network connectivity [PDF]
This study proposes a probabilistic approach for the quantitative assessment of reach- and network-scale hydrological connectivity as dictated by river flow space–time variability. Spatial dynamics of daily streamflows are estimated based on climatic and
Botter, Gianluca +3 more
core +1 more source
Robust estimation of spatially variable noise fields [PDF]
AbstractConsideration of spatially variable noise fields is becoming increasingly necessary in MRI given recent innovations in artifact identification and statistically driven image processing. Fast imaging methods enable study of difficult anatomical targets and improve image quality but also increase the spatial variability in the noise field ...
Landman, B. +3 more
openaire +3 more sources
Function‐driven design of a surrogate interleukin‐2 receptor ligand
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source

