Results 81 to 90 of about 1,207,920 (306)
Simple biophysics underpins collective conformations of the intrinsically disordered proteins of the Nuclear Pore Complex [PDF]
, 2016 Nuclear Pore Complexes (NPCs) are key cellular transporter that control nucleocytoplasmic transport in eukaryotic cells, but its transport mechanism is still not understood.
Coalson, Rob D. +7 more
core +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
IET Control Theory & Applications, 2021 The model identification and uncertain parameters estimation are common control problems in multi‐DOF manipulator system, since both model parametric uncertainties and unknown external disturbance often degrade the output performance and the close‐loop ...
Qing Guo, Zhenlei Chen, Yan Shi, Gan Liu
doaj +1 more source
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
On a multi-species Cahn-Hilliard-Darcy tumor growth model with singular potentials [PDF]
, 2017 We consider a model describing the evolution of a tumor inside a host tissue in terms of the parameters $\varphi_p$, $\varphi_d$ (proliferating and dead cells, respectively), $u$ (cell velocity) and $n$ (nutrient concentration). The variables $\varphi_p$,
Frigeri, Sergio +3 more
core +2 more sources
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Controls on spatial and temporal variability in streamflow and hydrochemistry in a glacierized catchment [PDF]
Hydrology and Earth System Sciences, 2018 Abstract. Understanding the hydrological and hydrochemical functioning of glacierized catchments requires the knowledge of the different controlling factors and their mutual interplay. For this purpose, the present study was carried out in two sub-catchments of the glacierized Sulden River catchment (130 km2; eastern Italian Alps) in 2014 and 2015 ...
Michael Engel +5 more
openaire +4 more sources
Dorsal root ganglion neurons maintained in a 3D culture model exhibit similar electrophysiological properties to fresh explants [PDF]
, 2011 Tissue engineered culture models provide a powerful tool for neuroscience research1. They overcome limitations associated with monolayer cultures of neurons and glia by maintaining cells in a more realistic 3D spatial arrangement, and permit continuous ...
East, E., Murphy, K., Phillips, J.
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
IET Control Theory & Applications, 2021 A fractional order sliding mode control (FOSMC) based on single parameter adaptive law for nano‐positioning of Piezoelectric Actuators (PEAs) is proposed.
Sai Zhang +3 more
doaj +1 more source