Results 81 to 90 of about 1,203,505 (306)
Dorsal root ganglion neurons maintained in a 3D culture model exhibit similar electrophysiological properties to fresh explants [PDF]
, 2011 Tissue engineered culture models provide a powerful tool for neuroscience research1. They overcome limitations associated with monolayer cultures of neurons and glia by maintaining cells in a more realistic 3D spatial arrangement, and permit continuous ...
East, E., Murphy, K., Phillips, J.
core
The spatial level of analysis affects the patterns of forest ecosystem services supply and their relationships [PDF]
, 2018 The implementation of the Ecosystem Services (ES) framework (including supply and demand) should be based on accurate spatial assessments to make it useful for land planning or environmental management.
Banqué-Casanovas, Mireia +8 more
core +3 more sources
Molecular Oncology, EarlyView.HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto +13 more
wiley +1 more source
Effect of chemotherapy on passenger mutations in metastatic colorectal cancer
Molecular Oncology, EarlyView.Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui +6 more
wiley +1 more source
The AIDS epidemic in the Amazon region: a spatial case-control study in Rondonia, Brazil
Revista de Saúde Pública, 2013 OBJECTIVE To analyze spatial changes in the risk of AIDS and the relationship between AIDS incidence and socioeconomic variables in the state of Rondonia, Amazon region.
Maria Rita Donalisio +3 more
doaj +1 more source
On the Control of Soil Heterogeneity, Peclet number and Spatially Variable Diffusion over Unsaturated Transport [PDF]
, 2022 Christopher V. Henri +1 more
openalex +1 more source
Molecular Oncology, EarlyView.Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad +12 more
wiley +1 more source
Institutions, geography, trade, and income per capita: A spatial-simultaneous equation approach [PDF]
This paper tests a series of prominent hypotheses regarding how institutions, geography, and trade interact to influence income per capita using a novel spatial econometric approach to control for both spillovers among neighboring countries and spatially
Ngeleza, Guyslain
core
Personality attributes that predict cadet performance at West Point [PDF]
, 2017 Using data from the United States Military Academy at West Point (N = 1102 and N = 1049) from two successive years, we examined psychological measures of cadets and the correlations of those measures with consequential outcomes such as cadet performance ...
Mayer, John D., Skimmyhorn, William
core +2 more sources
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source