Results 101 to 110 of about 1,973,931 (283)

THE CALIFORNIA ROCKFISH CONSERVATION AREA AND GROUNDFISH TRAWLERS AT MOSS LANDING HARBOR [PDF]

open access: yes
This article uses a bioeconomic model and data for groundfish trawlers at Moss Landing Harbor in Central California to analyze effects of spatial closures that were implemented recently by West Coast fishery managers to reduce bycatch of overfished ...
Dalton, Michael G., Ralston, Stephen
core   +1 more source

Using choice experiments to explore the spatial distribution of willingness to pay for rural landscape improvements [PDF]

open access: yes, 2007
We report findings from a choice experiment survey designed to estimate the economic benefits from policy measures which improve the rural landscape under an agri-environment scheme in the Republic of Ireland.
Campbell, Danny   +2 more
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Spatial variation of the length and humid weight of Limnoperna fortunei (Dunker, 1857) in Jacuí River Delta and Guaíba Lake Basin (Rio Grande do Sul State, Brazil) [PDF]

open access: yesBiotemas, 2008
Natural clusters of golden mussels (Limnoperna fortunei) were sampled in January 2005, in four stations of the Jacuí River Delta (Garças Creek (DAG) and Jacuí Channel (DCJ)) and Guaiba Lake (Veludo beach (GPV) and Pombas Pier (GPP)), in Rio Grande do Sul
Paulo Eduardo Aydos Bergonci   +5 more
doaj  

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Research on 2×2 MIMO Channel with Truncated Laplacian Azimuth Power Spectrum [PDF]

open access: yes, 2013
Multiple-input multiple-output (MIMO) Rayleigh fading channel with truncated Laplacian azimuth power spectrum (APS) is studied. By using the power correlation matrix of MIMO channel model and the modified Jakes simulator, into which with random phases ...
Wu, Q., Yang, X.-S., Zhang, Y.-T.
core   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Seafloor Characterization from Spatial Variation of Multibeam Backscatter vs. Best Estimated Grazing Angle [PDF]

open access: yes, 2002
Backscatter vs. grazing angle, which can be extracted from multibeam backscatter data, depends on characteristics of the multibeam system and the angular responses of backscatter that are characteristic of different seafloor properties, such as sediment ...
de Moustier, Christian   +3 more
core   +1 more source

Molecular characterisation of human penile carcinoma and generation of paired epithelial primary cell lines

open access: yesMolecular Oncology, EarlyView.
Generation of two normal and tumour (cancerous) paired human cell lines using an established tissue culture technique and their characterisation is described. Cell lines were characterised at cellular, protein, chromosome and gene expression levels and for HPV status.
Simon Broad   +12 more
wiley   +1 more source

Do the Growing Conditions of Trees Influence the Wood Properties?

open access: yesFloresta e Ambiente
Currently, there is a little and sparse information about how the growing conditions influence the spatial variation of wood along the stem. Thus, the aim of this study was to compile the knowledge from literature in a manuscript for better understanding
Maria Fernanda Vieira Rocha   +5 more
doaj   +1 more source

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