Results 111 to 120 of about 576,877 (314)
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Seasonal and Spatial Variation in Physico-Chemical
, 2018 One major socio-economic problem today is coping with increasing demand for water for domestic and other uses In most cases people depend on alternative means of supply such as rainwater harvesting collection from rivers streams and any available ...
Asikhia Monday, Ayeki Judith Aiwansosa
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Spatial and temporal trends in yield map data [PDF]
, 2004 As part of the research programme to develop precision farming management guidelines, started in 1995/96 on four sites in England, yield map data were recorded from 1995 onwards.
Blackmore, S. +3 more
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Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
, 2016 We studied spatial patterns in inundation water quality in a floodplain fen in Poland, resulting from interacting hydrological flow processes. Using PCA and K-means cluster analysis, we identified four clearly distinguishable water types, related to ...
Schot, P.P. +5 more
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Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
Weakening the nuclear envelope: Lamin B receptor in melanoma metastasis
Molecular Oncology, EarlyView.LBR‐driven nuclear fragility supports melanoma invasion. A: Melanocyte presents low LBR (Lamin B Receptor) levels, maintaining nuclear integrity and lamina‐chromatin tethering. B: During malignant progression, upregulation of LBR clusters at the INM (Inner Nuclear Membrane) during confined migration causes local lamina weakening and cholesterol ...
Francesca Lorenzini +1 more
wiley +1 more source
, 2015 Indonesia which is located in the equatorial region always received abundant of UV radiation throughout the year. Therefore, research concerning the impact of higher ultra violet-B radiation and its correlation with the total ozone and other component ...
Ninong Komala
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Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Changes in pollinator fauna cause spatial variation in pollen limitation
, 2010 1. Pollen limitation may be a consequence of changes in pollinator abundance, diversity and identity. However, no empirical evidence exists concerning the consequences that the spatial variation in pollinator fauna has on pollen limitation intensity and ...
Lorite, Juan +9 more
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