Results 101 to 110 of about 576,877 (314)

Spatial variation of the length and humid weight of Limnoperna fortunei (Dunker, 1857) in Jacuí River Delta and Guaíba Lake Basin (Rio Grande do Sul State, Brazil) [PDF]

open access: yesBiotemas, 2008
Natural clusters of golden mussels (Limnoperna fortunei) were sampled in January 2005, in four stations of the Jacuí River Delta (Garças Creek (DAG) and Jacuí Channel (DCJ)) and Guaiba Lake (Veludo beach (GPV) and Pombas Pier (GPP)), in Rio Grande do Sul
Paulo Eduardo Aydos Bergonci   +5 more
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Spatial variation of air pollutants in a multilevel office building

open access: yes, 2013
Within-building spatial variability of indoor air quality may influence substantially the reliability of human exposure assessments based on single point samples, but have hitherto been little studied.
Morawska, Lidia, He, Congrong
core  

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Do the Growing Conditions of Trees Influence the Wood Properties?

open access: yesFloresta e Ambiente
Currently, there is a little and sparse information about how the growing conditions influence the spatial variation of wood along the stem. Thus, the aim of this study was to compile the knowledge from literature in a manuscript for better understanding
Maria Fernanda Vieira Rocha   +5 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Spatial variation in functional group diversity in a sandflat benthic community: implications for ecosystem resilience

open access: yes, 2013
The resilience of macrobenthic communities to environmental stress depends upon the vulnerability, adaptability and connectivity of species. Recent studies suggest that the function(s) species perform may be more influential in driving community response
Greenfield, Barry Leon
core  

Modeling the Impact of Process Variation on Resistive Bridge Defects [PDF]

open access: yes, 2010
Recent research has shown that tests generated without taking process variation into account may lead to loss of test quality. At present there is no efficient device-level modeling technique that models the effect of process variation on resistive ...
Robert Aitken   +9 more
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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