Results 51 to 60 of about 4,617,927 (260)

Modelling stem cell differentiation related processes—A practical overview for biologists

FEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar, Xinqi Yan, Lucas F. Jansen Klomp, Stefano Schivo, Janine N. Post   +4 more
wiley   +1 more source

Spatial variation in soil properties and diffuse losses between and within grassland fields with similar short-term management [PDF]

, 2016
One of the major challenges for agriculture is to understand the effects of agricultural practices on soil properties and diffuse pollution, to support practical farm-scale land management. Three conventionally managed grassland fields with similar short-
P. J. Murray, R. E. Brazier, Peukert, S., Macleod, C. J. A., Brazier, R. E., S. Peukert, Murray, P. J., C. J. A. Macleod, Griffith, B. A., B. A. Griffith   +9 more
core   +1 more source

DNA-Based Identification and Chemical Characteristics of Hypnea musciformis from Coastal Sites in Ghana

Diversity, 2016
This work reveals new, important insights about the influence of broad spatial variations on the phylogenetic relationship and chemical characteristics of Ghanaian Hypnea musciformis—a carrageenan-containing red seaweed.
Marcel Tutor Ale, Kristian Barrett, Gloria Naa Dzama Addico, Nanna Rhein-Knudsen, Amoako Atta deGraft-Johnson, Anne S. Meyer   +5 more
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Spatial variation of particle number concentration in school microscale environments and its impact on exposure assessment [PDF]

, 2013
It has not yet been established whether the spatial variation of particle number concentration (PNC) within a microscale environment can have an effect on exposure estimation results.
Clifford, Sam, Morawska, Lidia, Salimi, Farhad, Laiman, Rusdin, Mazaheri, Mandana, Crilley, Leigh R.   +5 more
core   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Regional variation in the pronunciation of /s/ in the Dutch language area [PDF]

, 2019
This paper reports on an explorative sociophonetic study of the phoneme /s/ in the Dutch language area. Our aim is to investigate the regional variation in the realisation of this phoneme, and to test experimentally the observation of Collins & Mees ...
Heeren, W.F.L., Pinget, A.F., LS OZ Lexion en syntaxis, Ditewig, S., Pinget, A.C.H., ILS Variation, Ditewig, Sanne   +6 more
core   +2 more sources

Assessing Spatial Variation in Algal Productivity in a Tropical River Floodplain Using Satellite Remote Sensing

, 2021
Studies of tropical floodplains have shown that algae are the primary source material for higher consumers in freshwater aquatic habitats. Thus, methods that can predict the spatial variation of algal productivity provide an important input to better ...
Tim Malthus, Malthus, Tim J, Stuart Bunn, Bunn, Stuart E, Ben Stewart-Koster, Stewart-Koster, Ben, Molinari, Bianca, Bianca Molinari   +7 more
core   +1 more source

Influence of an Offshore Mussel Aquaculture Site on the Distribution of Epibenthic Macrofauna in Îles de la Madeleine, Eastern Canada

Frontiers in Marine Science, 2022
Mussel farming influences benthic environments by organic loading and the addition of physical structure within aquaculture leases. This study evaluated near-field (distance to mussel aquaculture structures, line-scale) and bay-scale (inside vs.
Anne-Sara Sean, Anne-Sara Sean, Annick Drouin, Annick Drouin, Philippe Archambault, Philippe Archambault, Christopher W. McKindsey, Christopher W. McKindsey, Christopher W. McKindsey   +8 more
doaj   +1 more source

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

FEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi, João C. Encarnação, Valeria Napolitano, Grzegorz Dubin, Grzegorz Popowicz, Karl Andersson, U. Helena Danielson   +6 more
wiley   +1 more source