Results 61 to 70 of about 4,617,927 (260)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Spatial and genetic epidemiology of hookworm in a rural community in Uganda. [PDF]

open access: yes, 2010
There are remarkably few contemporary, population-based studies of intestinal nematode infection for sub-Saharan Africa. This paper presents a comprehensive epidemiological analysis of hookworm infection intensity in a rural Ugandan community ...
Pullan, Rachel L   +18 more
core   +2 more sources

Distribución espacial de la macrofauna edáfica en bosque mesófilo, bosque secundario y pastizal en la reserva La Cortadura, Coatepec, Veracruz, México Spatial distribution of soil macrofauna in cloud forest, secondary forest and grassland in La Cortadura reserve, Coatepec, Veracruz, Mexico

open access: yesRevista Mexicana de Biodiversidad, 2012
La conversión de un área de bosque para la agricultura o el pastoreo homogeniza las propiedades del suelo y las comunidades de macroinvertebrados. Este trabajo estudió si la diversidad (H'), densidad y heterogeneidad espacial (tamaño de parche) de ...
Isis N. De la Rosa   +1 more
doaj  

Multispectral Remote Sensing Data Are Effective and Robust in Mapping Regional Forest Soil Organic Carbon Stocks in a Northeast Forest Region in China

open access: yesRemote Sensing, 2020
Accurately mapping the spatial distribution information of soil organic carbon (SOC) stocks is a key premise for soil resource management and environment protection.
Shuai Wang   +5 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Serological evidence of discrete spatial clusters of Plasmodium falciparum parasites. [PDF]

open access: yes, 2011
BACKGROUND: Malaria transmission may be considered to be homogenous with well-mixed parasite populations (as in the classic Ross/Macdonald models).
Cham, G   +59 more
core   +2 more sources

Coupling an aerosol box model with one-dimensional flow: a tool for understanding observations of new particle formation events

open access: yesTellus: Series B, Chemical and Physical Meteorology, 2016
Field observations of new particle formation and the subsequent particle growth are typically only possible at a fixed measurement location, and hence do not follow the temporal evolution of an air parcel in a Lagrangian sense.
Niku Kivekäs   +6 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

The role of edaphic, vegetational and spatial factors in structuring soil animal communities in a floodplain forest of the Dnipro river

open access: yesFolia Oecologica, 2018
This paper examines the role of ecological factors, derived from principal component analysis performed on edaphic and vegetational dataset as well as spatial variables, in structuring the soil macrofauna community of the Dnipro floodplain within the ...
Zhukov Oleksandr V.   +3 more
doaj   +1 more source

Spatial Variation of Leaf Chlorophyll in Northern Hemisphere Grasslands

open access: yesFrontiers in Plant Science, 2020
Chlorophyll is the molecular basis for the function of photosystems and is also a promising tool for ecological prediction. However, the large-scale patterns of chlorophyll variation in grasslands remain poorly understood.
Yao Zhang   +16 more
doaj   +1 more source

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