Results 51 to 60 of about 600,167 (284)
Function‐driven design of a surrogate interleukin‐2 receptor ligand
FEBS Letters, EarlyView.Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang +9 more
wiley +1 more source
Reward Expectation Differentially Modulates Global and Local Spatial Working Memory Accuracy
Frontiers in Psychology, 2021 Although it has been suggested that reward expectation affects the performance of spatial working memory tasks, controversial results have been found in previous experiments.
Qingjie Zhou, Zanzan Jiang, Jinhong Ding
doaj +1 more source
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Eye and hand movements during reconstruction of spatial memory [PDF]
, 2012 © 2012 a Pion publicationRecent behavioural and biological evidence indicates common mechanisms serving working memory and attention (e.g., Awh et al, 2006 Neuroscience 139 201-208).
Allen, RJ, Burke, MR, Gonzalez, C
core +2 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Research on Addiction, 2015 Objective: The present study was an attempt to examine the difference in the profile of working memory, auditory working memory, and spatial working memory between drug, stimulant, and methadone abusers and normal people.
Ahmad Alipour +2 more
doaj
Spatial working memory in visual search for multiple targets
Экспериментальная психология, 2017 The article investigated the role of spatial working memory in visual search for multiple targets, in particular, in subsequent search misses effect. This phenomenon is the second target omission after the first target has been found in visual
E.S. Gorbunova
doaj +1 more source
The temporary nature of number-space interactions [PDF]
, 2016 It is commonly accepted that the mental representation and processing of numbers and of space are tightly linked. This is evident from studies that have shown relations between math ability and visuospatial skill.
Fias, Wim, van Dijck, Jean-Philippe
core +2 more sources