Results 71 to 80 of about 8,055,585 (338)

Sparse spatial scaffolding for visual working memory

open access: yesThe Journal of Neuroscience, 2023
Abstract When holding information ‘in mind’, it is vital to keep individual representations separated and selectively accessible for behaviour. Space is known to serve as a foundational scaffold for mnemonic individuation, yet the format and flexibility of spatial scaffolding for working memory remain elusive.
Baiwei Liu   +4 more
openaire   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Effect of acute pesticide exposure on bee spatial working memory using an analogue of the radial-arm maze

open access: yesScientific Reports, 2016
Pesticides, including neonicotinoids, typically target pest insects by being neurotoxic. Inadvertent exposure to foraging insect pollinators is usually sub-lethal, but may affect cognition. One cognitive trait, spatial working memory, may be important in
Elizabeth E. W. Samuelson   +3 more
semanticscholar   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Spatial-sequential working memory in younger and older adults: age predicts backward recall performance within both age groups

open access: yesFrontiers in Psychology, 2016
Working memory is vulnerable to age-related decline, but there is debate regarding the age-sensitivity of different forms of spatial-sequential working memory task, depending on their passive or active nature.
Louise A. Brown
doaj   +1 more source

Traveling waves in the prefrontal cortex during working memory

open access: yesbioRxiv, 2022
Neural oscillations are evident across cortex but their spatial structure is not well-explored. Are oscillations stationary or do they form “traveling waves”, i.e., spatially organized patterns whose peaks and troughs move sequentially across cortex ...
Sayak Bhattacharya   +3 more
semanticscholar   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Working memory and its role in children’s scholastic attainment [PDF]

open access: yes, 2005
Previous research has identified links between working memory and scholastic skills. This thesis reports five studies that investigated both the role of working memory in children's scholastic attainment and the resources that underlie working memory ...
St Clair-Thompson, Helen
core  

Maintaining binding in working memory: Comparing the effects of intentional goals and incidental affordances [PDF]

open access: yes, 2011
Much research on memory for binding depends on incidental measures. However, if encoding associations benefits from conscious attention, then incidental measures of binding memory might not yield a sufficient understanding of how binding is accomplished.
Candice C. Morey, Morey, Candice C.
core   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

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