Results 81 to 90 of about 127,340 (313)

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Is Working Memory Necessary for Both Selection and Calculation in Level 1 Visual Perspective Taking? Evidence from Children and Adults

Behavioral Sciences
Previous research has suggested that there are two modular processes of perspective selection and calculation in level 1 perspective taking. Evidence further showed that verbal working memory is associated with both processes in adults. However, research
Guifen He, Wei Song, Peiqi Dong, Canmei Xu, Yanlin Zhou, Haoqin Ye, Qiong Zhang   +6 more
doaj   +1 more source

TgF344-AD Rat Model of Alzheimer’s Disease: Spatial Disorientation and Asymmetry in Hemispheric Neurodegeneration

Journal of Alzheimer's Disease Reports, 2023
Background: The TgF344-AD ratline represents a transgenic animal model of Alzheimer’s disease. We previously reported spatial memory impairment in TgF344-AD rats, yet the underlying mechanism remained unknown.
Boriss Sagalajev, Lina Lennartz, Lukas Vieth, Cecilia Tasya Gunawan, Bernd Neumaier, Alexander Drzezga, Veerle Visser-Vandewalle, Heike Endepols, Thibaut Sesia   +8 more
doaj   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source

Effect of Histamine on Muscimol-Induced Working Memory Deficits in Radial Maze Performance

Journal of Pharmacological Sciences, 2007
We investigated the participation of γ-aminobutyric acid (GABA) neurons of the medial septal area in eight-arm radial maze performance in rats. The intra-septal injection of muscimol, a GABAA agonist, caused an increase in total error and working memory ...
Yasuko Yamamoto, Azusa Mikami, Yoko Fujii, Chiaki Kamei   +3 more
doaj   +1 more source

Exploring the spatial working memory and visual perception in children with autism spectrum disorder and general population with high autism-like traits.

PLoS ONE, 2020
The aim of the study is to compare the spatial working memory and visual perception between children with autism spectrum disorder (ASD) and typically developing control (TDC).
Manxue Zhang, Jian Jiao, Xiao Hu, Pingyuan Yang, Yan Huang, Mingjing Situ, Kuifang Guo, Jia Cai, Yi Huang   +8 more
doaj   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

The Effect of Spatial Working Memory Deterioration on Strategic Visuomotor Learning across Aging

Behavioural Neurology, 2015
Objective. To evaluate the effect of age-related cognitive changes in a visuomotor learning task that depends on strategic control and contrast it with the effect in a task principally depending on visuomotor recalibration. Methods.
Luis A. Uresti-Cabrera, Rosalinda Diaz, Israel Vaca-Palomares, Juan Fernandez-Ruiz   +3 more
doaj   +1 more source

Creativity as Predictor of Mathematical Abilities in Fourth Graders in Addition to Number Sense and Working Memory

Journal of Numerical Cognition, 2017
In this study, it was investigated how domain-specific (number sense) and domain-general (working memory, creativity) factors explain the variance in mathematical abilities in primary school children.
Evelyn H. Kroesbergen, Eveline M. Schoevers   +1 more
doaj   +1 more source

The Effect of Cognitive Styles on Accuracy: the Role of Working Memory [PDF]

رشد و یادگیری حرکتی ورزشی, 2012
The present study aimed to examine throwing accuracy and spatial and digit working memory of field dependent-independent participants. The group embedded figure test (GEFT) was distributed among 320 male students and based on the GEFT scores, 45 ...
Ahmad Ghotbi-Varzaneh, Mehdi Zarghami, Esmaiel Saemi, Farzad Maleki   +3 more
doaj   +1 more source