Results 91 to 100 of about 14,742 (315)

From Mission to Church: Nature, Spatiality, and Catholicism in Kikwit (DRC)

open access: yesReligions
This study explores nature’s role in the spatial development of the local Roman Catholic Church in Kikwit, a mid-size city in the Democratic Republic of Congo.
Mick Feyaerts
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Processing postmodern spatiality

open access: yes, 2015
This paper is concerned with exploring the relation between movement and spatiality in the postmodern- of how we move, how we experience spatiality and the implications of such a relation.
Ng, Esther Xinlin
core  

The energy of spatiality [PDF]

open access: yes, 2017
Is it possible in our Belgian climate to realize highly energy efficient low-tech buildings with a natural ventilation strategy without heat recovery and heating system, similar to the prototype building be2226 build in Lustenau Austria in 2013 by the ...
Henz, Olivier
core  

Space as a tool for analysis: Examining digital learning spaces

open access: yesOpen Praxis, 2018
Over the past decade we have seen a rise in the adoption and proliferation of social technologies, and along with these a move to build on the capacity to embrace new pedagogies and practices that can open our boundaries for both teaching and learning ...
Michelle Harrison
doaj   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Surface pattern and spatiality

open access: yes, 2014
To investigate the relationships between surface pattern, spatiality and scale from the perspective of textile design. The research interest focuses on the explorations of textile patterns and spatiality, it also concerns documenting this as materials to
Kristensen Johnstone, Tonje,
core  

« L’art libérant l’architecture de la tyrannie de l’espace ». Autour de quelques textes d’Asger Jorn

open access: yesIn Situ, 2017
The following paper proposes to shed some light, from a novel angle, on the dialogue between art and architecture. It will not address the collaboration between an artist and an architect – or, if it does, only furtively; instead, it will analyse the way
Carmen Popescu
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

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