Results 81 to 90 of about 14,742 (315)

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

The lived spatiality of Ankara (1935-1950) through the memories of its citizens

open access: yes, 2008
As the capital of the young Turkish Republic, founded in 1923, Ankara was one of the few cities among its contemporaries that was constructed with a great deal of planning. It was the symbol of the nation-state and the modernisation of the city’s culture
Özaloğlu, Serpil
core  

Spectral spatiality in the acousmatic listening context [PDF]

open access: yes, 2012
Sounds are often experienced as being spatially higher or lower in congruence with their frequency ‘height’ (i.e. pitch register). The term ‘spectral spatiality’ refers to this impression of spatial height and vertical depth as evoked by the perceived ...
Khosravi, Peiman
core  

The Spatiality of Buddhism in Shenzhen: Exploration Through Guattari’s Three Ecologies

open access: yesJournal of Global Buddhism
This article explores the spatiality of Buddhism in the metropolis Shenzhen through its revitalization process in the past decades alongside the rapid expansion of the city.
Kai Shmushko
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

The choice of spatial scales and spatial smoothness priors for various spatial patterns

open access: yesSpatial and Spatio-temporal Epidemiology, 2014
Given the drawbacks for using geo-political areas in mapping outcomes unrelated to geo-politics, a compromise is to aggregate and analyse data at the grid level. This has the advantage of allowing spatial smoothing and modelling at a biologically or physically relevant scale.
Kang, Su   +2 more
openaire   +3 more sources

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Spatiality as Care: A Heideggerian Perspective on Sociomaterial Practices

open access: yes, 2017
The relationship between technological artefacts and the social settings of their design, production and use has received considerable attention in recent years, particularly through the emergence of the sociomateriality literature.
Eleni Lamprou
core   +1 more source

MULTIMODAL ANALYSIS ON SHOP SIGNS IN BANDA ACEH

open access: yesEnglish Education Journal: Jurnal Pengembangan Pendidikan dan Pengembangan Pengajaran Bahasa, 2020
This study is aimed at discovering the connotation and denotation that can be interpreted in shop signs found in Banda Aceh. Additionally, it also sought for the visuality, spatiality, and gestures that can be interpreted in shop sign found in Banda Aceh.
Yanti Zulita, Kismullah Abdul Muthalib
doaj  

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

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