Results 61 to 70 of about 3,005 (218)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

open access: yesFEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward   +2 more
wiley   +1 more source

Design principles for achieving spatiality in living space [PDF]

open access: yesArhitektura i Urbanizam, 2019
Achieving spatiality is one of the essential topics in designing living space meant to offer a higher level of space comfort. There are various methods to reach this objective: from neutralizing physical barriers in the interior, which would open the ...
Alfirević Đorđe   +1 more
doaj  

Space as a tool for analysis: Examining digital learning spaces

open access: yesOpen Praxis, 2018
Over the past decade we have seen a rise in the adoption and proliferation of social technologies, and along with these a move to build on the capacity to embrace new pedagogies and practices that can open our boundaries for both teaching and learning ...
Michelle Harrison
doaj   +1 more source

Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research

open access: yesFEBS Letters, EarlyView.
What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley   +1 more source

« L’art libérant l’architecture de la tyrannie de l’espace ». Autour de quelques textes d’Asger Jorn

open access: yesIn Situ, 2017
The following paper proposes to shed some light, from a novel angle, on the dialogue between art and architecture. It will not address the collaboration between an artist and an architect – or, if it does, only furtively; instead, it will analyse the way
Carmen Popescu
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Exploring the Timescape of Urban Camping Activities: A Case Study of Guangzhou

open access: yesRedai dili
In the post-pandemic period, urban camping has become a popular form of leisure in China. Such urban camping activities, which were originally "anti-everydayness", have infiltrated urban living spaces, forming an urban leisure landscape that differs from
Huang Yuhang, Liu Chen
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Cultures et politiques dans les Alpes contemporaines

open access: yesRevue de Géographie Alpine, 2008
More than ever before, the Alps are affected by increasingly varied and powerful flows and equally by the multiplication of initiatives designed to strengthen or regenerate the idea of “locality” (place).
Bernard Debarbieux
doaj   +1 more source

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