Results 61 to 70 of about 39,296 (293)

Brainstem and Cerebellar Volume Loss and Associated Clinical Features in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Progressive Supranuclear Palsy (PSP) is a neurodegenerative ‘tauopathy’ with predominating pathology in the basal ganglia and midbrain. Caudal tau spread frequently implicates the cerebellum; however, the pattern of atrophy remains equivocal.
Chloe Spiegel, Timothy P. Siejka, Cassandra Marotta, Josh J. Y. Lee, Kelly Bertram, Terence J. O'Brien, Meng Law, Lucy Vivash, Ian H. Harding   +8 more
wiley   +1 more source

Climate change and stream temperature projections in the Columbia River basin: habitat implications of spatial variation in hydrologic drivers [PDF]

Hydrology and Earth System Sciences, 2014
Water temperature is a primary physical factor regulating the persistence and distribution of aquatic taxa. Considering projected increases in air temperature and changes in precipitation in the coming century, accurate assessment of suitable thermal ...
D. L. Ficklin, B. L. Barnhart, J. H. Knouft, I. T. Stewart, E. P. Maurer, S. L. Letsinger, G. W. Whittaker   +6 more
doaj   +1 more source

Premixed Edge-Flames in Spatially-Varying Straining Flows [PDF]

Combustion Science and Technology, 1999
Flames subject to temporally and spatially uniform hydrodynamic strain are frequently used to model the local interactions of flame fronts with turbulent flow fields (Williams, 1985; Peters, 1986; Bradley, 1992). The applicability of laminar flamelet models in strongly turbulent flows have been questioned recently (Shay and Ronney, 1998) because in ...
JIAN-BANG LIU, PAUL D. RONNEY
openaire   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Geomorphometric Characterization of Pockmarks by Using a GIS-Based Semi-Automated Toolbox

Geosciences, 2018
Pockmarks are seabed depressions developed by fluid flow processes that can be found in vast numbers in many marine and lacustrine environments. Manual mapping of these features based on geophysical data is, however, extremely time-consuming and ...
Joana Gafeira, Margaret F. J. Dolan, Xavier Monteys   +2 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Structure–Function Decoupling of the Sensorimotor and Default Mode Networks in Black Americans With MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Objectives Multiple sclerosis (MS) exhibits racially disparate rates of disease progression. Black people with MS (B‐PwMS) experience a more severe disease course than non‐Hispanic White people with MS (NHW‐PwMS). Here we investigated structural and functional connectivity as well as structure–function decoupling in the ...
Emilio Cipriano, Giacomo Boffa, Maria Petracca, Marta Ponzano, Nicole Graziano, Claire Wigley, Claire Riley, Jonathan Howard, Pietro Bontempi, Sylvia Klineova, Fred Lublin, Matilde Inglese   +11 more
wiley   +1 more source

Quantifying spatial and temporal patterns of flow intermittency using spatially contiguous runoff data

, 2018
River channel drying caused by intermittent stream flow is a widely-recognized factor shaping stream ecosystems. There is a strong need to quantify the distribution of intermittent streams across catchments to inform management.
Mark J. Kennard, Bunn, Stuart E, Zongxue Xu, Bond, Nick R, Yu, Songyan, Bunn, Stuart, Kennard, Mark J, Stuart E. Bunn, Songyan Yu (于松延), Kennard, Mark, Xu, Zongxue, Bond, Nicholas, Nick R. Bond   +12 more
core   +1 more source

A note on critical flow section in collector channels [PDF]

, 2001
Generalized solution for the location of critical flow section in collector channels is presented. Based on the concept of the singularity, the dynamic equation of spatially varied flow (SVF) is solved using the flow resistance equations of von Karman ...
Dey, Subhasish
core   +1 more source

Validity of a Wearable Digital Insole for Assessing Gait ON and OFF in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Gait impairment is a distinctive symptom of Parkinson's disease that negatively impact mobility. We assessed the validity of wearable digital insoles against a validated reference gait analysis system for measuring select gait characteristics in patients with Parkinson's disease. Methods A comparative analysis between digital insoles
Deborah A. Hall, Kimberly Kwei, Rolando J. Acosta, Bharatkumar Koyani, Erin Robertson, Pratyush Rai, Roland Barge, Emily Timm, Nicollette L. Purcell, Natasha Desai, Dhanesh Patel, Ana‐Maria Visoiu‐Knapp, Samuel Stuart, Rinol Alaj, Matthew F. Wipperman, Oren Levy, Joan A. O'Keefe   +16 more
wiley   +1 more source