Results 11 to 20 of about 52 (24)

Human safety of SPBN GASGAS for oral rabies vaccination of dogs

PLoS Neglected Tropical Diseases
Oral rabies vaccination (ORV) of dogs has been suggested as a complementary tool to injectable rabies vaccination, to access free-roaming dogs during mass dog vaccination campaigns.
Ryan Wallace, Conrad Freuling, Gowri Yale   +2 more
exaly   +5 more sources

Comparable Long-Term Rabies Immunity in Foxes after IntraMuscular and Oral Application Using a Third-Generation Oral Rabies Virus Vaccine

Vaccines, 2021
The live genetically-engineered oral rabies virus (RABV) variant SPBN GASGAS induces long-lasting immunity in foxes and protection against challenge with an otherwise lethal dose of RABV field strains both after experimental oral and parenteral routes of
Luca M Zaeck, Stefan Finke
exaly   +3 more sources

Efficacy of the oral rabies virus vaccine strain SPBN GASGAS in foxes and raccoon dogs

Vaccine, 2019
To test the immunogenicity and efficacy of a new oral rabies virus vaccine strain SPBN GASGAS in wildlife target species, one group of foxes and two groups of raccoon dogs were offered a bait containing 1.7 ml of the vaccine (106.6 FFU/ml; 106.8 FFU/dose) and subsequently challenged approximately 180 days later with a fox rabies virus isolate.
Stefan Finke, , Conrad Freuling
exaly   +3 more sources

Emergency response using oral rabies vaccination of dogs –field data from Namibia demonstrate high efficiency

One Health, 2023
Dog-mediated rabies is responsible for tens of thousands of human deaths annually, and in resource-constrained settings, vaccinating dogs to control the disease at source remains challenging for various reasons. Currently, rabies elimination efforts rely
Conrad Freuling, Siegfried Khaiseb, Frank Busch   +2 more
exaly   +3 more sources

An assessment of shedding with the oral rabies virus vaccine strain SPBN GASGAS in target and non-target species

Vaccine, 2018
A safety requirement for live vaccines is investigating possible shedding in recipients since the presence of replication competent vaccine in secretions could result in direct and indirect horizontal transmission. This is especially relevant for oral rabies vaccine baits that are deliberately distributed into the environment.
, Conrad Freuling, Ad Voß
exaly   +3 more sources

Evaluation of Bait Acceptance and Immune Response in Local Dogs during an Oral Rabies Vaccination Field Study in Morocco

Tropical Medicine and Infectious Disease
The objective of this study was to evaluate the bait preference of three selected bait types by local dogs and the induced immunogenicity of the oral rabies vaccine strain SPBN GASGAS in Morocco.
Waśniewski Marine, Emmanuelle Robardet, Nadia Aboulfidaa   +2 more
exaly   +3 more sources

Feasibility of Oral Rabies Vaccination of Dogs in Mexico

Tropical Medicine and Infectious Disease
Mexico has not only successfully eliminated dog-mediated human rabies in recent years, but also the last rabies case in a dog infected with the canine variant of the rabies virus was reported in 2016.
Ad Voß, Voß Ad
exaly   +3 more sources

The Successful Elimination of Sylvatic Rabies Using Oral Vaccination of Foxes in Slovenia

Viruses, 2021
Sylvatic rabies was present in Slovenia between 1973 and 2013, with the red fox as the main reservoir of the rabies virus. The first oral rabies vaccination (ORV) control program in foxes started in 1988, using the manual distribution of baits ...
Danijela Černe, Peter Hostnik, Ivan Toplak   +2 more
doaj   +1 more source

Feasibility and Effectiveness Studies with Oral Vaccination of Free-Roaming Dogs against Rabies in Thailand

Viruses, 2021
(1) Background: Thailand has made significant progress in reducing the number of human and animal rabies cases. However, control and elimination of the last remaining pockets of dog-mediated rabies have shown to be burdensome, predominantly as a result ...
Karoon Chanachai, Vilaiporn Wongphruksasoong, Ad Vos, Kansuda Leelahapongsathon, Ratanaporn Tangwangvivat, Onpawee Sagarasaeranee, Paisin Lekcharoen, Porathip Trinuson, Suwicha Kasemsuwan   +8 more
doaj   +1 more source

Evaluation of Bait Acceptance and Immune Response in a Local Dog Population During an Oral Rabies Vaccination Field Study in Cambodia

Tropical Medicine and Infectious Disease
(1) Background: Dog-mediated human rabies remains a serious public health problem in Cambodia, partially due to the high abundance of dogs. As most dogs are free-roaming and cannot easily be handled and restrained, the rabies vaccination coverage is very
Bengthay Tep, Sochetra Hak, Nouv Sophorn, Sin Grandy, Ad Vos, Dim Kanan, Kinzang Dukpa   +6 more
doaj   +1 more source