Results 41 to 50 of about 421,690 (259)

Making Information About Cladribine Tablets Accessible to People with Multiple Sclerosis: A Patient-Survey-Led Narrative Review for Healthcare Professionals

open access: yesNeurology and Therapy
Cladribine tablets have been granted marketing authorization in Europe and approved by the Food and Drug Administration (FDA) in the USA to treat relapsing forms of multiple sclerosis (MS).
Ardra Shephard   +8 more
doaj   +1 more source

Ideologia diglosică în Republica Moldova

open access: yesLimbaj si Context, 2009
Any bilingual interaction involves language choice. It may depend on the sociolinguistic representations, which allow the speaker to relate his linguistic repertoire to his ethnic self-identification, insofar as he considers language an element of his ...
Marta Istrati
doaj   +1 more source

Variation at the Syntax–Pragmatics Interface: Discourse Particles in Questions

open access: yesLanguages, 2022
This paper focuses on the microvariation concerning the distribution and functions of certain interrogative discourse particles found in several central and southern Italian dialects.
Silvio Cruschina, Valentina Bianchi
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Performance Evaluation of The Speaker-Independent HMM-based Speech Synthesis System "HTS-2007" for the Blizzard Challenge 2007 [PDF]

open access: yes, 2008
This paper describes a speaker-independent/adaptive HMM-based speech synthesis system developed for the Blizzard Challenge 2007. The new system, named "HTS-2007", employs speaker adaptation (CSMAPLR+MAP), feature-space adaptive training, mixed-gender ...
Tokuda, Keiichi   +10 more
core   +1 more source

La référence à l'autorité dans la conversation

open access: yesCommunication, 2005
The objective of this article is to analyse the indexical function of the reference to authority juxtaposed with assertive acts in conversation. This then prolongs the work of the polyphonic school, which shed light on the function of modulation and ...
Martin David-Blais   +1 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Experimental and CFD Investigation of Wind-Induced Pressures on an 8° Gable Roof with Different Roof Opening Configurations

open access: yesJournal of Engineering
The research aims at studying the wind-induced pressure on an 8° low-slope gable roof by means of wind tunnel tests and ANSYS Fluent simulation analysis.
Ashraf Hameed Alsalmani   +1 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

On the effect of SNR and superdirective beamforming in speaker diarisation in meetings [PDF]

open access: yes, 2012
This paper examines the effect of sensor performance on speaker diarisation in meetings and investigates the use of more advanced beamforming techniques, beyond the typically employed delay-sum beamformer, for mitigating the effects of poorer sensor ...
Mike Lincoln   +5 more
core   +1 more source

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