Results 31 to 40 of about 43,494 (242)
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
A Review of State-of-the-Art Large Sized Foam Cutting Rapid Prototyping and Manufacturing Technologies. [PDF]
, 2010 Purpose – Current additive rapid prototyping (RP) technologies fail to efficiently produce objects greater than 0.5?m3 due to restrictions in build size, build time and cost. A need exists to develop RP and manufacturing technologies capable of producing
Aitchison, David +1 more
core +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
Mechanical properties and rock-breaking effects of ridge-shaped PDC teeth
Jin'gangshi yu moliao moju gongchengObjectives: With the depletion of easily recoverable oil reservoirs, the focus of oil and gas exploration and development in China has shifted to "two deeps and non-conventional" oil and gas fields.
Zhitao XIE +4 more
doaj +1 more source
Modeling dynamics and stability of 5-axis milling processes [PDF]
, 2007 5-axis milling is an important machining process for several industries such as aero-space, automotive and die/mold. It is mainly used in machining of sculptured surfaces where surface quality is of extreme importance.
Budak, Erhan +4 more
core
Molecular Oncology, EarlyView.Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Deployment mechanisms on Pioneer Venus probes [PDF]
, 1979 Deployment mechanisms were developed to position scientific instruments during probe descent into the Venus atmosphere. Each mechanism includes a provision for pyrotechnic release of the enclosure door, negator springs for positive deployment torque, and
Meadows, F. R. +2 more
core +1 more source
Biology and systematics of the New World Phyllocnistis Zeller leafminers of the avocado genus Persea (Lepidoptera, Gracillariidae) [PDF]
, 2011 Four New World species of Phyllocnistis Zeller are described from serpentine mines in Persea (Family Lauraceae). Phyllocnistis hyperpersea, new species, mines the upper leaf surfaces of avocado, Persea americana Mill., and red bay, Persea borbonia (L ...
Davis, Donald, Wagner, David
core +2 more sources
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source