Results 91 to 100 of about 2,930,954 (282)
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Optimizing Event-Driven Simulations
Event-driven molecular dynamics is a valuable tool in condensed and soft matter physics when particles can be modeled as hard objects or more generally if their interaction potential can be modeled in a stepwise fashion.
De Michele, Cristiano
core +1 more source
AAA+ protein unfoldases—the Moirai of the proteome
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley +1 more source
How Prediction Markets Can Save Event Studies [PDF]
This review paper articulates the relationship between prediction market data and event studies, with a special focus on applications in political economy.
Snowberg, Erik +2 more
core
In this talk we summarize the top physics setup in the event generator WHIZARD with a main focus on lepton colliders. This includes full six-, eight- and ten-fermion processes, factorized processes and spin correlations.
Bach, F. +7 more
core +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Special Issue: Hidden Criminalisation—Punitiveness at the Edges: Guest Editors’ Introduction
This special issue had its origins in a workshop on criminal law and criminalisation which we co-convened, and our law schools co-hosted, in 2017. That workshop was the fourth in what has become an annual event in Australia (starting with a Sydney Law ...
Julia Quilter, Luke McNamara
doaj +1 more source
Thin shell wormhole due to dyadosphere of a charged black hole
To explain Gamma Ray Bursts, Ruffini argued that the event horizon of a charged black hole is surrounded by a special region called, the Dyadosphere where electric field exceeds the critical value for $e^+$ $e^-$ pair production.
Daniels R. D. +4 more
core +1 more source
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source

