Results 51 to 60 of about 759,786 (310)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

Health sciences library outreach to family caregivers: a call to service

open access: yesJournal of the Medical Library Association, 2018
This commentary discusses the information needs of family caregivers and care recipients in the United States. Health sciences library services and outreach activities that support family caregivers include: (1) advocacy, (2) resource building, and (3 ...
Mary M. Howrey
doaj   +1 more source

Special Libraries, October 1944 [PDF]

open access: yes, 1944
Volume 35, Issue 8https://scholarworks.sjsu.edu/sla_sl_1944/1007/thumbnail ...
Special Libraries Association
core   +2 more sources

Navigating new norms: a systematic review of factors for the development of effective digital tools in higher education

open access: yesFEBS Open Bio, EarlyView.
What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman   +4 more
wiley   +1 more source

Information Outlook, July 1999 [PDF]

open access: yes, 1998
Volume 3, Issue 7https://scholarworks.sjsu.edu/sla_io_1999/1006/thumbnail ...
Special Libraries Association
core   +2 more sources

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

open access: yesFEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig   +7 more
wiley   +1 more source

Special Libraries, January 1921 [PDF]

open access: yes, 1920
Volume 12, Issue 1https://scholarworks.sjsu.edu/sla_sl_1921/1000/thumbnail ...
Special Libraries Association
core   +7 more sources

You Want Me To Do What? Lessons Learned from Mary Ellen Bates and the Special Library Trenches.

open access: yesIssues in Science and Technology Librarianship, 2009
The author addresses the future of special libraries. She comments on a lecture delivered by Mary Ellen Bates at the 2000 Special Libraries Association Annual Conference. She recommends that librarians think like entrepreneurs.
Laura L. Barnes
doaj   +1 more source

Special Libraries, February 1966 [PDF]

open access: yes, 1964
Volume 57, Issue 2https://scholarworks.sjsu.edu/sla_sl_1966/1001/thumbnail ...
Special Libraries Association
core   +4 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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