Results 81 to 90 of about 172,492 (313)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Axion mass bound in very special relativity

open access: yesPhysics Letters B, 2017
In this paper we propose a very special relativity (VSR)-inspired description of the axion electrodynamics. This proposal is based upon the construction of a proper study of the SIM(2)–VSR gauge-symmetry.
R. Bufalo, S. Upadhyay
doaj   +1 more source

Measuring Electromagnetic Fields in Rotating Frames of Reference

open access: yesUniverse, 2020
We review the problem of transforming electromagnetic fields between inertial and rotating reference frames. We compare the method of straightforward tensor coordinate transformations adopted by Schiff in his well-known paper of 1939 with the method of ...
Clive C. Speake, Antonello Ortolan
doaj   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

open access: yesMolecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz   +12 more
wiley   +1 more source

Testing fundamental physics with photon frequency shift

open access: yesEuropean Physical Journal C: Particles and Fields, 2020
We propose a high precision satellite experiment to further test Einstein’s General Relativity and constrain extended theories of gravity. We consider the frequency shift of a photon radially exchanged between two observers located on Earth and on a ...
Luca Buoninfante   +2 more
doaj   +1 more source

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

open access: yesMolecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir   +12 more
wiley   +1 more source

Unruh effect of nonlocal field theories with a minimal length

open access: yesPhysics Letters B, 2018
The nonlocal field theory commonly requires a minimal length, and so it appears to formulate the nonlocal theory in terms of the doubly special relativity which makes the speed of light and the minimal length invariant simultaneously. We set up a generic
Yongwan Gim, Hwajin Um, Wontae Kim
doaj   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

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