Results 91 to 100 of about 4,019,418 (288)

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

open access: yesMolecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge   +17 more
wiley   +1 more source

COVID-19-Related and general racial discrimination and mental health in Asian Americans

open access: yesBMC Public Health
Background Although reports indicate Asian Americans (AA) experienced racial discrimination during the COVID-19 pandemic, there exists a research gap that adequately details the nature and influence of racial discrimination on the mental health of AAs ...
Qiuxi Li   +6 more
doaj   +1 more source

SPECIAL TREATMENT, 2018. Vol. 3. (1.)

open access: yesKülönleges Bánásmód, 2017
Special Treatment, 2017. Vol. 3.
Bánásmód Különleges
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

SPECIAL TREATMENT, 2019. Vol. 5. (1.)

open access: yesKülönleges Bánásmód, 2019
Special Treatment, 2019. Vol. 5.
Bánásmód Különleges
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra   +6 more
wiley   +1 more source

Surgical myectomy might inhibit ascending aortic dilation in obstructive hypertrophic cardiomyopathy: a serial cardiac magnetic resonance study

open access: yesJournal of Cardiothoracic Surgery
Background The impact of septal myectomy on the progression of ascending aortic (AAo) dilation in patients with obstructive hypertrophic cardiomyopathy (HOCM) remains uncertain. This study aimed to investigate the relationship between septal myectomy and
Changpeng Song   +6 more
doaj   +1 more source

Inconsistent Objectives of Agricultural Export Credit Disciplines [PDF]

open access: yes
Negotiated disciplines on export credits in agriculture are intended to (1) eliminate any subsidy element caused by preferential financing or low fees and (2) provide special and differential treatment for developing countries.
Thompson, Wyatt
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Myocardial bridging in obstructive hypertrophic cardiomyopathy: a risk factor for myocardial fibrosis

open access: yesBMC Medicine
Background Myocardial bridging (MB) is common in patients with hypertrophic cardiomyopathy (HCM). There are sparse data on the impact of MB on myocardial fibrosis in HCM.
Changpeng Song   +10 more
doaj   +1 more source

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