Results 91 to 100 of about 1,228,724 (306)

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Laparoscopic versus open distal pancreatectomy: A meta-analysis

open access: yesAsian Journal of Surgery, 2012
Objective: Laparoscopic distal pancreatectomy (LDP) is a minimally invasive surgical technique. The aim of the present study was to evaluate the currently available literature and compare the short-term clinical outcomes of patients who underwent LDP for
Cheng-Jun Sui   +4 more
doaj   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

KÜLÖNLEGES BÁNÁSMÓD, 2017. 3. (2.)

open access: yes, 2017
Special Treatment, 2017. Vol. 3. (2.) - full textKülönleges Bánásmód, 2017. 3.
Special, Treatment   +1 more
core   +1 more source

Special and Differential Treatment, The Multilateral Trading System and Economic Development in the 21st Century

open access: yes
This paper was prepared for the joint ICTSD – GP International Dialogue entitled, Making Special & Differential Treatment More Effective and Responsive to Development Needs, held 6 & 7 May 2003, in Chavannes-de-bogis, Switzerland.Economic ...
Singh, Ajit
core   +2 more sources

COVID-19-Related and general racial discrimination and mental health in Asian Americans

open access: yesBMC Public Health
Background Although reports indicate Asian Americans (AA) experienced racial discrimination during the COVID-19 pandemic, there exists a research gap that adequately details the nature and influence of racial discrimination on the mental health of AAs ...
Qiuxi Li   +6 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

Funding vaccines for emerging infectious diseases

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Immunization has played a large role in substantially reducing the infected and death tolls from infectious diseases. In the case of emerging diseases, the identity of the pathogen responsible, as well as the time and location for the next outbreak ...
Gary Wong, Xiangguo Qiu
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

KÜLÖNLEGES BÁNÁSMÓD, 2017. 3. (4.)

open access: yes, 2017
Special Treatment, 2017. Vol. 3. (4.) - full textKülönleges Bánásmód, 2017. 3.
Special, Treatment   +1 more
core   +1 more source

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