Results 101 to 110 of about 15,123,411 (350)

A Novel Nomogram for Predicting Warfarin-Related Bleeding: A Retrospective Cohort Study

Clinical and Applied Thrombosis/Hemostasis
Warfarin is a widely used anticoagulant, and bleeding complications are the main reason why patients discontinue the drug. Currently, there is no nomogram model for warfarin-associated bleeding risk. The aim of this study was to develop a risk-prediction
Shaohua Yang MD, Wensen Yao MD
doaj   +1 more source

Observation and factor analysis of submucosal injection of dexamethasone for analgesia and detumescence after incremental bone implantation [PDF]

Kouqiang yixue
Objective To study the efficacy of submucosal injection of dexamethasone in analgesia and detumescence after incremental bone implantation, and to analyze the related factors of pain and swelling after incremental bone implantation. Methods Patients with
HE Feng, ZHU Hong, ZHU Wenqing
doaj   +1 more source

Some Observations ON THE BACTERIOLOGY AND VACCINE TREATMENT OF CHRONIC BRONCHITIS: Based on 300 Cases, with Special Reference to Associated Nasal Infections [PDF]

, 1922
L. Mackey
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

A Discussion on Syphilis, with Special Reference to (a) its Prevalence and Intensity in the Past and at the Present Day; (b) its Relation to Public Health, Including Congenital Syphilis; (c) the Treatment of the Disease [PDF]

, 1912
C. F. Marshall
  +5 more sources

The impact of gut microbial signals on hematopoietic stem cells and the bone marrow microenvironment

Frontiers in Immunology
Hematopoietic stem cells (HSCs) undergo self-renewal and differentiation in the bone marrow, which is tightly regulated by cues from the microenvironment.
Xiru Liu, Xiru Liu, Xiru Liu, Hao Zhang, Hao Zhang, Hao Zhang, Guolin Shi, Guolin Shi, Guolin Shi, Xinmin Zheng, Xinmin Zheng, Xinmin Zheng, Jing Chang, Jing Chang, Jing Chang, Jing Chang, Quande Lin, Zhenhao Tian, Zhenhao Tian, Zhenhao Tian, Hui Yang, Hui Yang, Hui Yang   +22 more
doaj   +1 more source

Time, the final frontier

Molecular Oncology, EarlyView.
This article advocates integrating temporal dynamics into cancer research. Rather than relying on static snapshots, researchers should increasingly consider adopting dynamic methods—such as live imaging, temporal omics, and liquid biopsies—to track how tumors evolve over time.
Gautier Follain, Michal Dibus, Omkar Joshi, Guillaume Jacquemet   +3 more
wiley   +1 more source

THE ETIOLOGY AND TREATMENT OF DIABETES: With Special Reference to the Significance of a Starchsplitting and Acetone-forming Organism Found in the Stools of Diabetic Patients [PDF]

, 1922
A. Renshaw, T. H. Fairbrother
openalex   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

Molecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson, Emma L. Dorward, Kristyn Jurrius, Nathalie Nataren, Markus Tondl, Kay K. Myo Min, Michaelia P. Cockshell, Anahita Fouladzadeh, John Toubia, Mark DeNichilo, Delphine Merino, Claudine S. Bonder   +11 more
wiley   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source