Results 41 to 50 of about 1,164,136 (338)

Epidemiology and clinical study of phenylketonuria (PKU) patients in Khorasan Province; Norteast Iran [PDF]

open access: yesIranian Journal of Neonatology, 2015
Epidemiology and clinical study of phenylketonuria (PKU) patients in Khorasan Province; Norteast Iran Background: Phenylketonuria is an autosomal recessive disease.
Negar Morovatdar   +4 more
doaj   +1 more source

Iatrogenic panhypopituitarism: how many puzzles you need to solve on your way to pregnancy: a clinical case

open access: yesActa Biomedica Scientifica, 2018
Introduction. Iatrogenic panhypopituitarism requires specific approaches to infertility treatment, prenatal care and childbearing. Aim: to show difficulties and peculiarities of infertility treatment of a patient with iatrogenic panhypopituitarism ...
S. Manojlovic   +2 more
doaj   +1 more source

Making tau amyloid models in vitro: a crucial and underestimated challenge

open access: yesFEBS Letters, EarlyView.
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley   +1 more source

Expression Characteristics, Immune Signature, and Prognostic Value of the SOCS Family Identified by Multiomics Integrative Analysis in Liver Cancer

open access: yesCancer Reports
Background Hepatocellular carcinoma (HCC) is a prevalent malignancy with a high mortality rate worldwide. Suppressor of cytokine signaling (SOCS) family members play important roles in the proliferation, metabolism, and immunity of HCC cells by ...
Zhitao Dong   +6 more
doaj   +1 more source

Special conditions in the treatment of hemorrhoidal disease. The advantages of THD-RAR in the treatment of hemorrhoidal disease in these situations [PDF]

open access: yesRomanian Medical Journal, 2020
Introduction. The prevalence of hemorrhoids in the general population ranks first among benign anorectal diseases. In the last 20 years, however, the number of cases operated for hemorrhoidal disease has decreased and consequently the experience of ...
Romica Mehic   +4 more
doaj   +1 more source

TREATMENT OF PERNICIOUS ANEMIA BY A SPECIAL DIET [PDF]

open access: yesBlood, 1926
Abstract The dietetic treatment of pernicious anemia is of more importance than hitherto generally recognized. Forty-five patients with pernicious anemia observed essentially in sequence are continuing to take a special diet that they have now been living on for from about six weeks to two years but which was temporarily ...
George R. Minot, William P. Murphy
openaire   +4 more sources

Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms

open access: yesFEBS Letters, EarlyView.
Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze   +3 more
wiley   +1 more source

circFN1 Mediates Sorafenib Resistance of Hepatocellular Carcinoma Cells by Sponging miR-1205 and Regulating E2F1 Expression

open access: yesMolecular Therapy: Nucleic Acids, 2020
In recent years, circular RNAs (circRNAs) have been shown to have critical regulatory roles in the resistance to anti-cancer drugs. However, the contributions of circRNAs to sorafenib resistance in hepatocellular carcinoma (HCC) remain largely unknown ...
Cheng Yang   +9 more
doaj  

Infrahepatic inferior vena cava clamping in hepatectomy for tumors involving hepatocaval confluence

open access: yesAsian Journal of Surgery, 2013
Background: Massive hemorrhage and the need for blood transfusion carry a high rate of morbidity and mortality after hepatectomy. The aim of this study was to evaluate the safety and potential benefit of infrahepatic inferior vena cava (IVC) clamping in ...
Jiamei Yang   +4 more
doaj   +1 more source

Tetramethylpyrazine protects rat astrocytes against H2O2-induced oxidative stress injury

open access: yesDi-san junyi daxue xuebao, 2021
Objective To investigate the protective effect of tetramethylprazine (TMP) on oxidative stress injury induced by hydrogen peroxide (H2O2) in rat astrocytes.
YANG Qin   +6 more
doaj   +1 more source

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