Results 71 to 80 of about 4,022,746 (290)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Laparoscopic versus open distal pancreatectomy: A meta-analysis

open access: yesAsian Journal of Surgery, 2012
Objective: Laparoscopic distal pancreatectomy (LDP) is a minimally invasive surgical technique. The aim of the present study was to evaluate the currently available literature and compare the short-term clinical outcomes of patients who underwent LDP for
Cheng-Jun Sui   +4 more
doaj   +1 more source

Two-Loop Effects and Current Status of the 4He+ Lamb Shift

open access: yes, 2007
We report on recent progress in the treatment of two-loop binding corrections to the Lamb shift, with a special emphasis on S and P states. We use these and other results in order to infer an updated theoretical value of the Lamb shift in 4He+.Comment ...
Beier P.J.   +31 more
core   +1 more source

Neuromodulation in neurogenic bladder. [PDF]

open access: yes, 2016
While neuromodulation is a well-established treatment option for patients with non-neurogenic overactive bladder and urinary retention, its applicability to the neurogenic bladder population has only recently been examined more in depth.
Sanford, Melissa T, Suskind, Anne M
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Condensation of Ideal Bose Gas Confined in a Box Within a Canonical Ensemble

open access: yes, 2007
We set up recursion relations for the partition function and the ground-state occupancy for a fixed number of non-interacting bosons confined in a square box potential and determine the temperature dependence of the specific heat and the particle number ...
A. Einstein   +15 more
core   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

Special and Differential Treatment in the WTO Agricultural Negotiations [PDF]

open access: yes
This paper examines the case for special and differential (S&D) treatment for developing countries within the WTO Agreement on Agriculture and the particular instruments or exemptions it should contain.
Alan Matthews
core  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Funding vaccines for emerging infectious diseases

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Immunization has played a large role in substantially reducing the infected and death tolls from infectious diseases. In the case of emerging diseases, the identity of the pathogen responsible, as well as the time and location for the next outbreak ...
Gary Wong, Xiangguo Qiu
doaj   +1 more source

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