Results 91 to 100 of about 99,252 (304)

Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati, Sami I. Nassar, Shaun A. Nguyen, Patricia L. Gerend, Michael C. Schubert, Michael T. Teixido, Frederick A. Godley, Joel A. Goebel, Cynthia A. Ryan, Habib G. Rizk, Amir Kheradmand   +10 more
wiley   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

Annals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao, Qiu‐Ping Zhao, Run‐Yun Li, Wei Chen, Huan‐Huan Song, Wan‐Jin Chen, Ying Fu   +6 more
wiley   +1 more source

Advanced Nursing Practice in New Zealand: 1998

Nursing Praxis in Aotearoa New Zealand, 1998
In the last decade, change in the health sector has often seemed to deny and thwart the professionalism and expertise of nurses.  However, in the first half of 1998, a number of positive initiatives have come to fruition, which support the development of
Susan Jacobs
doaj   +1 more source

Mothers’ Preventive Measures of COVID-19 among Their Primary School Children [PDF]

Egyptian Journal of Health Care
Background: In epidemics such as COVID-19, major changes need to be made to the population's behavior to prevent infection and stop disease transmission.
Eman Ibrahim Mohamed Eltantawy, Magda Abd El Sattar Ahmed, Shaimaa Fathy Miky   +2 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Durable mechanical circulatory support in paediatric heart failure: The experience at Great Ormond Street Hospital

Cirugía Cardiovascular, 2019
Durable ventricular assist devices (VAD), despite being a standard therapy for adults in end-stage heart failure, are not so extended among the paediatric population for some reasons.
Ana Redondo, Ben Davies, Rebecca Jones, Maura O’Callaghan, Martin Kostolny   +4 more
doaj   +1 more source

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

Heart failure nurse specialist crisis interventions and avoided hospital admissions

, 2015
This service evaluation identified the crisis interventions carried out by a heart failure nurse specialist working across the acute and primary care sector of a rural Trust which resulted in avoided hospital admissions.
McLaughlin , Donna, Hoy, Leonita, Glackin, Marie   +2 more
core   +1 more source

Status quo of certification，recognition，and practice in the field of pain specialist nurse in China and United States

Huli yanjiu, 2018
This article reviewed the status quo of certification，recognition，and practice on pain management nurses(PMN) and advanced practicepain management nurse (APPMN) in the United States and pain specialist nurse in China.It pointed out that the relevant ...
Chen Jiajia, TONG Yingge, Chai Ling, et al   +3 more
doaj