Results 101 to 110 of about 661,671 (286)

Single‐Cell Dissection of Therapy‐Induced Remodeling Uncovers a Fibroblast‐Driven Immunosuppressive Niche and Targetable Vulnerabilities in Lethal Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Single‐cell longitudinal profiling reveals that androgen‐deprivation therapy induces a DPT+ fibroblast‐complement axis that suppresses macrophage inflammation and drives CD8+ T cell exhaustion in prostate cancer. Concurrently, resistant epithelial subpopulations persist and engage TSPAN1‐ and NRXN1‐mediated programs promoting CRPC and neuroendocrine ...
Yang Chen   +19 more
wiley   +1 more source

Pre‐Regenerative Endothelial Cells Empowered by Antler Blood Exosomes Orchestrate Peripheral Nerve Repair

open access: yesAdvanced Science, EarlyView.
The pre‐regenerative vascular niche (PVN) is essential for nerve repair, yet its endothelial blueprint remains unclear. We identified angiogenic ECs (AECs) as the dominant pre‐regenerative subset and found that antler blood–derived exosomes (AB‐EXO) promote repair via IMP3.
Jinsheng Huang   +11 more
wiley   +1 more source

Views on implementing nurse prescribing in a specialist children's hospital

open access: yes, 2020
This study aimed to explore the views of health care professionals on the implementation of nurse prescribing in a specialist children's hospital. An intrinsic case study approach was taken using thematic analysis on semi-structured interview data ...
Stenner, KL, Carey, N, Courtenay, M
core  

Research progress on related factors of core competencies of nurse specialist in operation room

open access: yesHuli yanjiu, 2017
This paper reviewed definition of core competence,research status quo of nurses’ core competencies and influencing factors of core competencies of nurse specialist in operation room,so as to provide suggestions for improving core competence of nurse ...
刘晓凤, 邓露, 王惠平, 申海艳
doaj  

Specialist Nurses in Gastroenterology [PDF]

open access: yesJournal of the Royal Society of Medicine, 2002
Norton, C, Kamm, M A
openaire   +2 more sources

Iron‐Mediated Release of Aged Dissolved Organic Carbon From Waterlogged Peatland Under Warming

open access: yesAdvanced Science, EarlyView.
This study conducts a five‐year in situ warming experiment in high‐altitude peatlands to examine dissolved organic carbon (DOC) release. The study shows that warming promotes the release of plant‐derived modern DOC in drained peatlands, but amplifies aquatic export of century‐old DOC from waterlogged peatlands via Fe‐mediated DOC mobilization—a ...
Guohua Dai   +18 more
wiley   +1 more source

RNAi in the Rhizarian Phytopathogen Plasmodiophora brassicae: The Causal Agent of Clubroot Disease in Cruciferous Crops

open access: yesAdvanced Science, EarlyView.
This study uncovers an unusual RNAi pathway in the rhizarian pathogen Plasmodiophora brassicae. In the absence of Dicer, a Drosha‐like RNase III protein supports the biogenesis of predominant 21‐nt small RNAs, and two Argonaute proteins mediate small RNA‐guided silencing.
Xiong Zhang   +13 more
wiley   +1 more source

The Clinical Nurse Specialist in New Zealand: How Is the Role Defined? [PDF]

open access: yes, 2011
New Zealand, like many countries, is developing new advanced nursing practice roles to meet emerging needs. While much has been written about the Nurse Practitioner (NP), the role of Clinical Nurse Specialist (CNS) remains relatively unexplored and lacks
Jennifer Roberts   +2 more
core  

Overcoming Artificial Structures in Resolution‐Enhanced Hi‐C Data by Signal Decomposition and Multi‐Scale Attention

open access: yesAdvanced Science, EarlyView.
Deep‐learning‐based signal enhancement is an effective way to recover high‐resolution details from a low‐resolution chromatin contact map. However, due to computational challenges, existing methods commonly divide up the contact map into small patches and create artificial discontinuities at patch boundaries.
Qinyao Li   +6 more
wiley   +1 more source

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