Results 131 to 140 of about 262,521 (313)
Specialisms in the Special Constabulary [PDF]
, 2019 Special Constables undertaking more specialised policing roles, serving in specialist teams and developing specialist skill-sets, is not an entirely new phenomenon. There has however been significant growth over recent years in the scale and breadth of such ‘specialist’ Special Constabulary roles. This represents an important development in the growing
Britton, Iain +3 more
openaire
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
BMC Cardiovascular DisordersBackground Pregnant women with mechanical heart valves (MHVs) require continuous anticoagulation; however, first-trimester exposure to warfarin raises concerns regarding fetal safety.
Sule Arici +12 more
doaj +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Export Productivity and Specialization in China, Brazil, India and South Africa [PDF]
This paper analyses the patterns of export productivity and trade specialization profiles in the China, Brazil, India and South Africa, and in other regional groupings.
Santos-Paulino, Amelia U.
core
Sport Specialization Status and Athlete Burnout, Engagement, and Motivation
, 2023 Early sport specialization, in which athletes compete in one sport nearly year round at a young age, is common in today's athletic culture. Several national sport organizations advise against early specialization due to its potentially increasing the ...
NC DOCKS at East Carolina University +1 more
core
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
PRODUCTIVE SPECIALIZATION AND REGIONAL DEVELOPMENT IN PORTUGAL AT THE NUTS III LEVEL [PDF]
The purpose of this paper is to analyse how the specialization of Portuguese productive structures has evolved between 1995 and 2004, using specialization indicators, namely localization quotient estimation, to assess both the relative degree of ...
Francisco Diniz
core
Current OncologyBackground: Hematooncology patients admitted to intensive care units (ICUs) are at high risk for mortality due to the severity of their critical illness.
Jhon H. Quintana +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley +1 more source