Results 31 to 40 of about 823,640 (389)
Regional studies, 2019 This paper examines the ways by which organizational and institutional features of regional innovation systems shape smart specialization practices in less-developed, intermediate and advanced regions.
Michaela Trippl +2 more
semanticscholar +1 more source
Cold Ironing: Socio-Economic Analysis in the Port of Genoa
Logistics, 2023 Background: The emissions of ships in ports are increasingly becoming an issue, and particularly those of NOx, SOx, and PM, rather than CO2. One realistic solution for reducing GHG emissions is cold ironing technology.
Monica Canepa +4 more
doaj +1 more source
Sport Specialization and Risk of Overuse Injuries: A Systematic Review With Meta-analysis
Pediatrics, 2018 This study is a systematic review of the relationship between sport specialization and overuse injury risk. CONTEXT: Sport specialization is theorized to increase the risk of sustaining overuse musculoskeletal injuries.
D. Bell +4 more
semanticscholar +1 more source
BMC Urology, 2018 Background To investigate the efficacy of tamsulosin in patients with lower urinary tract symptoms (LUTS) and benign prostatic enlargement (BPE) with intravesical prostatic protrusion (IPP). Ultrasound measurement of the IPP has been previously described
L. Topazio +7 more
doaj +1 more source
Sports Specialization and Intensive Training in Young Athletes
Pediatrics, 2016 Sports specialization is becoming the norm in youth sports for a variety of reasons. When sports specialization occurs too early, detrimental effects may occur, both physically and psychologically.
J. Brenner
semanticscholar +1 more source
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FEBS Letters, EarlyView.FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac +3 more
wiley +1 more source
Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia
FEBS Letters, EarlyView.This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley +1 more source
Biology, 2023 Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that debilitates over 55 million individuals worldwide. Currently, treatments manage and alleviate its symptoms; however, there is still a need to find a therapy that prevents or halts ...
Mackayla L. Nelson +4 more
doaj +1 more source
AOSSM Early Sport Specialization Consensus Statement
Orthopaedic Journal of Sports Medicine, 2016 Background: Early sport specialization is not a requirement for success at the highest levels of competition and is believed to be unhealthy physically and mentally for young athletes.
R. LaPrade +16 more
semanticscholar +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source