Results 51 to 60 of about 697,557 (339)

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

FEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan, Victoria Scarpelli, Marten Exterkate   +2 more
wiley   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

FEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

A Practical Approach to SARS-CoV-2 Prevention and Containment in a National Sporting Event in Italy: A Public Health Model Applicable Also to Other Respiratory Viruses?

COVID
The Italian sporting event ‘XIV Convittiadi’ involving students at boarding schools took place in Molise region, central Italy, in April 2022. The study describes the public health protocol with specific countermeasures developed for the event, including
Roberta De Dona, Manuela Tamburro, Carmen Adesso, Angelo Salzo, Antonio D’Amico, Nicandro Samprati, Arturo Santagata, Michela Anna Di Palma, Anna Natale, Fabio Cannizzaro, Vittorio Viccione, Giancarlo Ripabelli   +11 more
doaj   +1 more source

The Simple Chordate Has a Reduced Complement of Genes Associated with Fanconi Anemia

Evolutionary Bioinformatics, 2016
Fanconi anemia (FA) is a human genetic disease characterized by congenital defects, bone marrow failure, and increased cancer risk. FA is associated with mutation in one of 24 genes.
Edward C. Stanley, Paul A. Azzinaro, David A. Vierra, Niall G. Howlett, Steven Q. Irvine   +4 more
doaj   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

FEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Actinomycosis: Mimicking Malignancies in Multiple Anatomical Sites—A Three-Patient Case Series

Medicina
Background and Objectives: Actinomycosis is a rare chronic contagion caused by Actinomyces spp. known for its ability to mimic malignant processes across various anatomical locations.
John Fernando Montenegro, Vanessa Correa Forero, Yamil Liscano, Andres Grueso Pineda, Diana Marcela Bonilla Bonilla, Paola Andrea Ruiz Jimenez   +5 more
doaj   +1 more source

Hospitalizations for pneumonia, invasive diseases and otitis in Tuscany (Italy), 2002-2014: Which was the impact of universal pneumococcal pediatric vaccination?

Human Vaccines & Immunotherapeutics, 2017
Streptococcus pneumoniae is the main causative organism of acute media otitis in children and meningitis and bacterial pneumonia in the community. Since 2008 in Tuscany, central Italy, the pneumococcal conjugate vaccine (7-valent vaccine, switched to 13 ...
Sara Boccalini, Ornella Varone, Martina Chellini, Luca Pieri, Antonino Sala, Cesare Berardi, Paolo Bonanni, Angela Bechini   +7 more
doaj   +1 more source

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

SPECIAL IS AS SPECIAL DOES

RBM: A Journal of Rare Books, Manuscripts, and Cultural Heritage, 2000
Nothing is very special in the least about special collections unless they are made meaningful. The meaning derives from the interaction of the artifact and the individual mind and heart; Rachel Howarth, in a companion piece to this one, has provided many examples of such encounters.
openaire   +3 more sources

Novel and unscrutinized immune entities of the zebrafish gut

FEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil, Marine Mantel, Julia Soh, Serge Mostowy, Sylvia Brugman, Gilles Claude Vanwalleghem   +5 more
wiley   +1 more source