Results 1 to 10 of about 501,668 (378)
γδ T, NKT, and MAIT Cells During Evolution: Redundancy or Specialized Functions? [PDF]
The Journal of Immunology, 2022 Innate-like T cells display characteristics of both innate lymphoid cells (ILCs) and mainstream αβ T cells, leading to overlapping functions of innate-like T cells with both subsets.
Christelle Harly +3 more
semanticscholar +5 more sources
Zinc networks: the cell-specific compartmentalization of zinc for specialized functions [PDF]
bchm, 2012 Abstract Zinc (Zn2+) is the most abundant trace element in cells and is essential for a vast number of catalytic, structural, and regulatory processes. Mounting evidence indicates that like calcium (Ca2+), intracellular Zn2+ pools are redistributed for specific cellular functions.
Stephen R. Hennigar, Shannon L. Kelleher
semanticscholar +5 more sources
eLife, 2014 Mesenchymal stem cells (MSCs) and osteolineage cells contribute to the hematopoietic stem cell (HSC) niche in the bone marrow of long bones. However, their developmental relationships remain unclear.
Joan Isern +7 more
openalex +2 more sources
Proceedings of the National Academy of Sciences of the United States of America, 1976 Armin Braun, Henry N. Wood
openalex +2 more sources
Deubiquitinase USP1 influences the dedifferentiation of mouse pancreatic β-cells
iScience, 2023 Summary: Loss of insulin-secreting β-cells in diabetes may be either due to apoptosis or dedifferentiation of β-cell mass. The ubiquitin-proteasome system comprising E3 ligase and deubiquitinases (DUBs) controls several aspects of β-cell functions.
Meenal Francis +5 more
doaj +1 more source
iScience, 2023 Summary: Adipose tissue from pheochromocytoma patients acquires brown fat features, making it a valuable model for studying the mechanisms that control thermogenic adipose plasticity in humans. Transcriptomic analyses revealed a massive downregulation of
Moisés Castellá +18 more
doaj +1 more source
Characterization of adipose depot-specific stromal cell populations by single-cell mass cytometry
iScience, 2022 Summary: The increased prevalence of obesity and metabolic diseases has heightened interest in adipose tissue biology and its potential as a therapeutic target.
Ju Hee Lee +7 more
doaj +1 more source
iScience, 2023 Summary: Platelets have a great ability to modulate immune responses. Monocyte-platelet aggregates (MPAs) are associated with the pathogenesis of cardiac disease.
Wei-Yun Shen +6 more
doaj +1 more source
A ligand-receptor interactome atlas of the zebrafish
iScience, 2023 Summary: Studies in zebrafish can unravel the functions of cellular communication and thus identify novel bench-to-bedside drugs targeting cellular communication signaling molecules.
Milosz Chodkowski +2 more
doaj +1 more source