Results 101 to 110 of about 501,668 (378)

Blood Vessels and Vascular Niches in Bone Development and Physiological Remodeling

open access: yesFrontiers in Cell and Developmental Biology, 2020
Recent advances in our understanding of blood vessels and vascular niches in bone convey their critical importance in regulating bone development and physiology.
Michelle Hendriks   +3 more
doaj   +1 more source

Intestinal stem cell proliferation and epithelial homeostasis in the adult Drosophila midgut [PDF]

open access: yes, 2015
Adult tissue homeostasis requires a tight balance between the removal of old or damaged cells and the production of new ones. Such processes are usually driven by dedicated stem cells that reside within specific tissue locations or niches.
Carroll, Lynsey   +2 more
core   +1 more source

Specialized Functional Diversity and Interactions of the Na,K-ATPase

open access: yesFrontiers in Physiology, 2016
Na,K-ATPase is a protein ubiquitously expressed in the plasma membrane of all animal cells and vitally essential for their functions. A specialized functional diversity of the Na,K-ATPase isozymes is provided by molecular heterogeneity, distinct ...
V. Matchkov, I. Krivoi
semanticscholar   +1 more source

Novel and unscrutinized immune entities of the zebrafish gut

open access: yesFEBS Letters, EarlyView.
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil   +5 more
wiley   +1 more source

Retinoic acid as a modulator of T cell immunity [PDF]

open access: yes, 2016
Indexación: Scopus. DOAJ.Vitamin A, a generic designation for an array of organic molecules that includes retinal, retinol and retinoic acid, is an essential nutrient needed in a wide array of aspects including the proper functioning of the visual system,
Bono, M.R.   +5 more
core   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

open access: yesFEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker   +9 more
wiley   +1 more source

Exposure of Pancreatic β-Cells to Excess Glucose Results in Bimodal Activation of mTORC1 and mTOR-Dependent Metabolic Acceleration

open access: yesiScience, 2020
Summary: Chronic exposure of pancreatic β-cells to excess glucose can lead to metabolic acceleration and loss of stimulus-secretion coupling. Here, we examined how exposure to excess glucose (defined here as concentrations above 5 mM) affects mTORC1 ...
Courtney Zasha Rumala   +5 more
doaj   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

The pyramidal cell in cognition: A comparative study in human and monkey [PDF]

open access: yes, 2001
Here we present evidence that the pyramidal cell phenotype varies markedly in the cortex of different anthropoid species. Regional and species differences in the size of, number of bifurcations in, and spine density of the basal dendritic arbors cannot ...
Benavides-Piccione, Ruth   +2 more
core   +1 more source

Metabolic Hallmarks of Hepatic Stellate Cells in Liver Fibrosis

open access: yesCells, 2019
Liver fibrosis is a regenerative process that occurs after injury. It is characterized by the deposition of connective tissue by specialized fibroblasts and concomitant proliferative responses.
O. Khomich, A. Ivanov, B. Bartosch
semanticscholar   +1 more source

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