Results 21 to 30 of about 501,668 (378)
Control of lymphocyte functions by gut microbiota-derived short-chain fatty acids
Cellular & Molecular Immunology, 2021 A mounting body of evidence indicates that dietary fiber (DF) metabolites produced by commensal bacteria play essential roles in balancing the immune system. DF, considered nonessential nutrients in the past, is now considered to be necessary to maintain
Chang H. Kim
semanticscholar +1 more source
Functional Specialization of Skin Dendritic Cell Subsets in Regulating T Cell Responses [PDF]
Frontiers in Immunology, 2015 Dendritic cells (DC) are a heterogeneous family of professional antigen-presenting cells classically recognized as most potent inducers of adaptive immune responses. In this respect, Langerhans cells have long been considered to be prototypic immunogenic DC in the skin. More recently this view has considerably changed.
Patrizia Stoitzner, Björn E. Clausen
openaire +4 more sources
Lens regeneration in situ using hESCs-derived cells —similar to natural lens
iScience, 2023 Summary: Lens itself has limited regeneration functionality, thus we aimed to create regenerated lens with biological function to treat cataracts rather than the intraocular lens used in cataract surgery.
Xinyi Chen +9 more
doaj +1 more source
iScience, 2023 Summary: Hepcidin is the master hormone governing systemic iron homeostasis. Iron regulates hepcidin by activating bone morphogenetic protein (BMP)6 expression in liver endothelial cells (LECs), but the mechanisms are incompletely understood.
Allison L. Fisher +9 more
doaj +1 more source
Antigen-presenting cells as specialized drivers of intestinal T cell functions
ImmunityThe immune system recognizes a multitude of innocuous antigens from food and intestinal commensal microbes toward which it orchestrates appropriate, non-inflammatory responses. This process requires antigen-presenting cells (APCs) that induce T cells with either regulatory or effector functions.
Ranit Kedmi, Dan R. Littman
openalex +3 more sources
The plant-pathogen haustorial interface at a glance [PDF]
, 2020 Many filamentous pathogens invade plant cells through specialized hyphae called haustoria. These infection structures are enveloped by a newly synthesized plant-derived membrane called the extrahaustorial membrane (EHM).
Bozkurt, Tolga O., Kamoun, Sophien
core +1 more source
iScience, 2023 Summary: The FliG protein plays a pivotal role in switching the rotational direction of the flagellar motor between clockwise and counterclockwise. Although we previously showed that mutations in the Gly-Gly linker of FliG induce a defect in switching ...
Tatsuro Nishikino +6 more
doaj +1 more source
Effect of mitophagy in the formation of osteomorphs derived from osteoclasts
iScience, 2023 Summary: Osteoclasts are specialized multinucleated giant cells with unique bone-destroying capacities. A recent study revealed that osteoclasts undergo an alternative cell fate by dividing into daughter cells called osteomorphs. To date, no studies have
Tingben Huang +9 more
doaj +1 more source
iScience, 2020 Summary: Ca2+ oscillations that depend on inositol-1,4,5-trisphosphate (IP3) have been ascribed to biphasic Ca2+ regulation of the IP3 receptor (IP3R) or feedback mechanisms controlling IP3 levels in different cell types.
Paula J. Bartlett +3 more
doaj +1 more source
Optogenetic activation of UCP1-dependent thermogenesis in brown adipocytes
iScience, 2023 Summary: Brown adipocytes are unique in that they expend energy and produce heat to maintain euthermia through expression of uncoupling protein-1 (UCP1).
Chad C. Doucette +9 more
doaj +1 more source