Modularity map of the network of human cell differentiation [PDF]
Cell differentiation in multicellular organisms is a complex process whose mechanism can be understood by a reductionist approach, in which the individual processes that control the generation of different cell types are identified.
Anglani +20 more
core +2 more sources
Functional maturation during bovine granulopoiesis [PDF]
Granulocytic precursor cells undergo morphologic changes in the nucleus and the cytoplasm during the process of granulopoiesis, which takes place in the bone marrow.
Burvenich, Christian +2 more
core +2 more sources
Meeting report: a hard look at the state of enamel research. [PDF]
The Encouraging Novel Amelogenesis Models and Ex vivo cell Lines (ENAMEL) Development workshop was held on 23 June 2017 at the Bethesda headquarters of the National Institute of Dental and Craniofacial Research (NIDCR).
Bartlett, John D +13 more
core +1 more source
Hippocampal Global Remapping Can Occur without Input from the Medial Entorhinal Cortex. [PDF]
The high storage capacity of the episodic memory system relies on distinct representations for events that are separated in time and space. The spatial component of these computations includes the formation of independent maps by hippocampal place cells ...
Boublil, Brittney L +4 more
core +2 more sources
Container network functions: bringing NFV to the network edge [PDF]
In order to cope with the increasing network utilization driven by new mobile clients, and to satisfy demand for new network services and performance guarantees, telecommunication service providers are exploiting virtualization over their network by ...
Cziva, Richard, Pezaros, Dimitrios P.
core +1 more source
AMPKα2 is a skeletal muscle stem cell intrinsic regulator of myonuclear accretion
Summary: Due to the post-mitotic nature of skeletal muscle fibers, adult muscle maintenance relies on dedicated muscle stem cells (MuSCs). In most physiological contexts, MuSCs support myofiber homeostasis by contributing to myonuclear accretion, which ...
Anita Kneppers +10 more
doaj +1 more source
Functional specialization of gut CD103 + dendritic cells in the regulation of tissue-selective T cell homing [PDF]
Gut-associated lymphoid tissue (GALT) dendritic cells (DCs) display a unique ability to generate CCR9+α4β7+ gut-tropic CD8+ effector T cells. We demonstrate efficient induction of CCR9 and α4β7 on CD8+ T cells in mesenteric lymph nodes (MLNs) after oral but not intraperitoneal (i.p.) antigen administration indicating differential targeting of DCs via ...
Johansson-Lindbom, Bengt +6 more
openaire +2 more sources
Cleaved intracellular SNARE peptides are implicated in a novel cytotoxicity mechanism of botulinum serotype C [PDF]
Recent advances in intracellular protein delivery have enabled more in-depth analyses of cellular functions. A specialized family of SNARE proteases, known as Botulinum Neurotoxins, blocks neurotransmitter exocytosis, which leads to systemic toxicity ...
Arsenault, Jason +5 more
core +1 more source
Multiple Functions of Malpighian Tubules in Insects: A Review
The Malpighian Tubules (MTs) are the main excretory organs in most insects. They play a key role in the production of primary urine and osmoregulation, selectively reabsorbing water, ions, and solutes.
Priscilla Farina +2 more
doaj +1 more source
Co-Emergence of Specialized Endothelial Cells from Embryonic Stem Cells. [PDF]
A well-formed and robust vasculature is critical to the health of most organ systems in the body. However, the endothelial cells (ECs) forming the vasculature can exhibit a number of distinct functional subphenotypes like arterial or venous ECs, as well ...
Douglas, Simone A +6 more
core +1 more source

