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Specialized pro-resolving lipid mediators in gut immunophysiology: from dietary precursors to inflammation resolution [PDF]

Current opinion in clinical nutrition and metabolic care
Purpose of review This review aims to examine recent research on the role of specialized pro-resolving mediators (SPMs) in the regulation of gut immunophysiology.
Emmanuel Albuquerque-Souza, Jesmond Dalli   +1 more
semanticscholar   +2 more sources

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Anti-inflammatory celastrol promotes a switch from leukotriene biosynthesis to formation of specialized pro-resolving lipid mediators.

Pharmacological Research, 2021
The pentacyclic triterpenoid quinone methide celastrol (CS) from Tripterygium wilfordii Hook. F. effectively ameliorates inflammation with potential as therapeutics for inflammatory diseases.
S. Pace, Kehong Zhang, P. M. Jordan, Rossella Bilancia, Wen-Fei Wang, Friedemann R. Börner, R. Hofstetter, M. Potenza, C. Kretzer, J. Gerstmeier, D. Fischer, S. Lorkowski, N. Gilbert, M. Newcomer, A. Rossi, Xin-Chun Chen, O. Werz   +16 more
semanticscholar   +1 more source

N-3 PUFAs and their specialized pro-resolving lipid mediators on airway inflammatory response: beneficial effects in the prevention and treatment of respiratory diseases.

Food & Function, 2022
Respiratory diseases include a wide range of pathologies with different clinical manifestations, affecting the normal airways and lung function. An increase in the inflammatory response is considered a characteristic hallmark of these diseases, being ...
J. Zúñiga-Hernández, V. Sambra, F. Echeverría, L. Videla, R. Valenzuela   +4 more
semanticscholar   +1 more source

Specialized Pro-resolving Lipid Mediators

Encyclopedia of Molecular Pharmacology, 2021

semanticscholar   +1 more source

Challenges and Prospects for Clinical Application of Specialized Pro-resolving Lipid Mediators and Their Synthetic Analogues in Atherosclerosis.

Current Medicinal Chemistry
Atherosclerosis, a major cause of cardiovascular diseases, has a complex pathogenesis involving lipid metabolism disorders and chronic inflammation in the vascular wall.
S. Kotlyarov
semanticscholar   +1 more source

Specialized pro-resolving lipid mediators in experimental periodontitis: A systematic review.

Oral Diseases, 2018
Recently, several studies demonstrated the potential of using specialized pro-resolving lipid mediators (SPMs), as a novel approach, in treating periodontitis in pre-clinical models.
Marcela M. Osorio Parra, S. Elangovan, Chun-Teh Lee   +2 more
semanticscholar   +1 more source

EPA and DHA differentially modulate monocyte inflammatory response in subjects with chronic inflammation in part via plasma specialized pro-resolving lipid mediators: A randomized, double-blind, crossover study

Atherosclerosis, 2021
Albert K Tai, Alice H. Lichtenstein, Nirupa R Matthan   +2 more
exaly  

Effect of specialized pro-resolving lipid mediators in the regulation of vascular tone and inflammation in human saphenous vein

Prostaglandins and Other Lipid Mediators, 2023
Ali Aycan Kavala, Gokce Topal, Zeynep Çelik   +2 more
exaly  

Inflammation resolution and specialized pro-resolving lipid mediators in CNS diseases

Expert Opinion on Therapeutic Targets, 2019
Di Ma, Meiying Xin, Pei Shang
exaly  

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Frontiers in Immunology, 2020
Chun-Teh Lee, Nikola Angelov, Srinivas Ayilavarapu   +2 more
exaly