Results 71 to 80 of about 63,195 (262)

Correlated patterns of genetic diversity and differentiation across an avian family [PDF]

, 2017
Comparative studies of closely related taxa can provide insights into the evolutionary forces that shape genome evolution and the prevalence of convergent molecular evolution.
Campagna, Leonardo, Helm, Barbara, Illera, Juan Carlos, Liedvogel, Miriam, Lovette, Irby J., Van Doren, Benjamin M.   +5 more
core   +1 more source

Genome-Wide Congealing and Rapid Transitions across the Speciation Continuum during Speciation with Gene Flow [PDF]

Journal of Heredity, 2014
Our current understanding of speciation is often based on considering a relatively small number of genes, sometimes in isolation of one another. Here, we describe a possible emergent genome process involving the aggregate effect of many genes contributing to the evolution of reproductive isolation across the speciation continuum.
Jeffrey L, Feder, Patrik, Nosil, Aaron C, Wacholder, Scott P, Egan, Stewart H, Berlocher, Samuel M, Flaxman   +5 more
openaire   +2 more sources

Divergent Roles of mGlu2 and mGlu3 Receptors in Amyloid‐β Production and Cognitive Dysfunctions in Alzheimer's Disease

Advanced Science, EarlyView.
This study explores the opposing effects of the mGluR2 and mGluR3 receptors on amyloid precursor protein processing. mGluR2 promotes amyloidogenic cleavage, while mGluR3 favors non‐amyloidogenic pathways. Using a brain‐penetrant nanobody as a mGluR2 positive allosteric modulator, the study uncovers how its chronic activation aggravates amyloid‐β burden
Pierre‐André Lafon, Mireille Elodie Tsitokana, Ugo Guy Alenda, Yen‐Ling Lian, Clémentine Eva Philibert, Mathieu Oosterlaken, Marta Cimadevila, Gaëlle Dudon, Jessica Monnic, Salomé Roux, Julie Bessié, Séverine Diem, Franck Vandermoere, Laurent Prézeau, Patrick Chames, Julie Kniazeff, Sylvie Claeysen, Anaïs Menny, Jean‐Philippe Pin, Véronique Perrier, Jianfeng Liu, Philippe Rondard   +21 more
wiley   +1 more source

Genomics of Evolutionary Novelty in Hybrids and Polyploids

Frontiers in Genetics, 2020
It has long been recognized that hybridization and polyploidy are prominent processes in plant evolution. Although classically recognized as significant in speciation and adaptation, recognition of the importance of interspecific gene flow has ...
Gonzalo Nieto Feliner, Josep Casacuberta, Jonathan F. Wendel   +2 more
doaj   +1 more source

A new species in the major malaria vector complex sheds light on reticulated species evolution [PDF]

, 2019
Complexes of closely related species provide key insights into the rapid and independent evolution of adaptive traits. Here, we described and studied Anopheles fontenillei sp.n., a new species in the Anopheles gambiae complex that we recently discovered ...
Akone-Ella O., Ayala D., Barron M. G., Costantini C., Gonzalez J., Kengne P., Ngangue M. F., Paupy C., Pombi M., Rahola N., Simard F., Wilson-Bahun T. A.   +11 more
core   +1 more source

Advanced Dental Composite Technology via Bisilanized Dual‐Action Nanofillers for Biofilm Control

Advanced Science, EarlyView.
A multimodal research strategy has led to the development of an innovative resin‐based composite (RBC) with dual antibacterial action. The S_CM‐RBC formula showed strong antibiofilm activity, excellent mechanical strength, and biosafety. It effectively controlled oral bacteria in prevention of caries recurrence, and maintained pulp health in a rat ...
Chenmin Yao, Line Etiennot, Naiera Zayed, Shengjie Liang, Mehraveh Saghi, Jelle Verdonck, Lingyue Liu, Fei Zhang, Wim Teughels, Cui Huang, Kirsten Van Landuyt, Bart Van Meerbeek   +11 more
wiley   +1 more source

Ancient polymorphisms and divergence hitchhiking contribute to genomic islands of divergence within a poplar species complex [PDF]

, 2017
How genome divergence eventually leads to speciation is a topic of prime evolutionary interest. Genomic islands of elevated divergence are frequently reported between diverging lineages, and their size is expected to increase with time and gene flow ...
Abbott, Richard John, Ahani, Hamid, Feng, Jianju, Hu, Quanjun, Jiang, Dechun, Lascoux, Martin, Liu, Jianquan, Ma, Tao, Nevo, Eviatar, Wan, Dongshi, Wang, Kun, Wang, Qian, Xi, Zhenxiang   +12 more
core   +1 more source

Waves of Colonization and Gene Flow in a Great Speciator

Systematic Biology
Abstract Secondary contact between previously allopatric lineages offers a test of reproductive isolating mechanisms that may have accrued in isolation. Such instances of contact can produce stable hybrid zones—where reproductive isolation can further develop via reinforcement or phenotypic displacement—or result in the lineages ...
Ethan F. Gyllenhaal, Serina S. Brady, Lucas H. DeCicco, Alivereti Naikatini, Paul M. Hime, Joseph D. Manthey, John Kelly, Robert G. Moyle, Michael J. Andersen   +8 more
openaire   +3 more sources

A Catalytic Osmium Redox Couple Collapses Cancer Redox Balance

Advanced Science, EarlyView.
A stable Os(III)/Os(IV) redox couple is developed to disrupt the tumor cell redox balance by concurrently catalyzing ROS generation and GSH depletion. Osmium‐treated cells exhibit multiple cell death pathways, including apoptosis, ferroptosis, and immunogenic cell death.
Wan‐Qiong Huang, Tao Huang, Yiming Hao, Gui‐Feng Huang, Yi‐Lang Yan, Xin Fang, Ying Chen, Xiao‐Long Wei, Wai‐Lun Man, Wen‐Xiu Ni   +9 more
wiley   +1 more source

Cryptic species? Patterns of maternal and paternal gene flow in eight neotropical bats. [PDF]

PLoS ONE, 2011
Levels of sequence divergence at mitochondrial loci are frequently used in phylogeographic analysis and species delimitation though single marker systems cannot assess bi-parental gene flow.
Elizabeth L Clare
doaj   +1 more source