Results 101 to 110 of about 10,839,218 (369)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Thalassiosira punctigera. Niet-inheemse soorten van het Belgisch deel van de Noordzee en aanpalende estuaria [PDF]

, 2011
Thalassiosira punctigera is een kiezelwier of diatomee waarvan het oorsprongsgebied niet echt gekend is. Er wordt verondersteld dat de soort samen met getransporteerde kweekoesters of via ballastwater naar Europa gekomen is omstreeks 1978.
VLIZ Alien Species Consortium
core  

Growth Factors Outside of the Platelet-derived Growth Factor (PDGF) Family Employ Reactive Oxygen Species/Src Family Kinases to Activate PDGF Receptor α and Thereby Promote Proliferation and Survival of Cells [PDF]

, 2009
Hetian Lei, Andrius Kazlauskas
openalex   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

Molecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga, María Luz Martinez‐Chantar, Carolina Conter   +2 more
wiley   +1 more source

Assessing the Hibernation Ecology of the Endangered Amphibian, Pelophylax chosenicus Using PIT Tagging Method

Animals
The Gold-spotted pond frog (Pelophylax chosenicus (Okada, 1931)), classified as an endangered species in South Korea, has experienced significant population declines due to habitat loss, primarily driven by agricultural expansion and urbanization.
Kwanik Kwon, Changdeuk Park, Jeongwoo Yoo, Nakyung Yoo, Keun-Sik Kim, Juduk Yoon   +5 more
doaj   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Violet buiswier - Neosiphonia harveyi. Niet-inheemse soorten van het Belgisch deel van de Noordzee en aanpalende estuaria [PDF]

, 2011
Het violet buiswier Neosiphonia harveyi kwam oorspronkelijk enkel voor rond Japan, in het noorden van de Stille Oceaan. Waarschijnlijk kwam deze exoot samen met getransporteerde oesters en via vasthechting op andere wieren of scheepsrompen naar Europa ...
VLIZ Alien Species Consortium
core  

RELATIONSHIP BETWEEN SELF-FERTILITY, ALLOCATION OF GROWTH, AND INBREEDING DEPRESSION IN THREE CONIFEROUS SPECIES [PDF]

, 1999
Frank C. Sorensen
openalex   +1 more source

Specie not species [PDF]

Nature, 1990
openaire   +1 more source