Results 131 to 140 of about 6,022,549 (302)

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

open access: yesFEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez   +6 more
wiley   +1 more source

Predicting climate change impacts on poikilotherms using physiologically guided species abundance models. [PDF]

open access: yesProc Natl Acad Sci U S A, 2023
Wagner T   +6 more
europepmc   +1 more source

Identifying and characterising a plant GH1 β‐glucosidase that exhibits hydrolytic activity on N‐linked glucopyranoside

open access: yesFEBS Open Bio, EarlyView.
We report the first β‐glucosidase with demonstrated hydrolytic activity on an N‐linked glycopyranoside. The enzyme, native to maize, was biochemically characterised for this novel reaction, and structural modelling of the enzyme–substrate complex revealed several clues to the underlying reduced catalytic rate relative to its native O‐glycopyranoside ...
Hani Gharabli   +3 more
wiley   +1 more source

Leaf Fungal Endophyte Differs Among Plant Functional Groups in an Alpine Meadow

open access: yesEcology and Evolution
Although numerous studies have documented the differences in leaf fungal endophyte (LFE) communities among various plant species inhabiting the same environments, the disparities in LFE among distinct species groups have rarely been examined at the ...
Miao Dong   +3 more
doaj   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

open access: yesFEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Effectiveness of territorial protection categories in conserving an endemic island bird during population fluctuation

open access: yesConservation Science and Practice
Protected areas represent cornerstones of biodiversity conservation on oceanic islands, yet their effectiveness for endemic species remains poorly evaluated.
Luis M. Carrascal   +2 more
doaj   +1 more source

ON THE RELATIVE ABUNDANCE OF BIRD SPECIES [PDF]

open access: yesProceedings of the National Academy of Sciences, 1957
openaire   +2 more sources

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

open access: yesFEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti   +5 more
wiley   +1 more source

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