Assessing predictive accuracy of species abundance models in dynamic systems
Methods in Ecology and EvolutionCascading human pressures and environmental change are affecting the natural dynamics of animal populations. Forecasting population abundances from time‐series data provides an important avenue for testing competing ecological theories and for supporting
Christopher J. Brown +5 more
doaj +1 more source
Species abundance correlations carry limited information about microbial network interactions. [PDF]
PLoS Comput Biol, 2022 Pinto S +4 more
europepmc +1 more source
Species abundance, urn models, and neutrality
Comptes Rendus. BiologiesThe neutral theory of biodiversity and biogeography has stimulated much research in community ecology. Here, exact results are used to apply neutral model predictions to large regional samples. Three complementary neutral models are presented: the Ewens canonical neutral model, a model of subdivided ecological communities, and a ...
openaire +4 more sources
Aging Is a Key Driver for Adult Acute Myeloid Leukemia
Aging and Cancer, EarlyView.Acute myeloid leukemia (AML) is a classical age‐related hematologic malignancy, and a key driver of AML is aging, which profoundly regulates intrinsic factors such as genomic instability, epigenetic reprogramming, and metabolic dysregulation, and alters bone marrow microenvironment.
Rong Yin, Haojian Zhang
wiley +1 more source
Review of Anopheles Mosquito Species, Abundance, and Distribution in Ethiopia. [PDF]
J Trop Med, 2021 Adugna F, Wale M, Nibret E.
europepmc +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
Analyzing dynamic species abundance distributions using generalized linear mixed models. [PDF]
Ecology, 2022 Solbu EB +3 more
europepmc +1 more source
RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu +21 more
wiley +1 more source
The Effects of Species Abundance, Spatial Distribution, and Phylogeny on a Plant-Ectomycorrhizal Fungal Network. [PDF]
Front Plant Sci, 2022 Zhu C +7 more
europepmc +1 more source
Augmenting and Assaying Nav1.1 Protein Quantity for Dravet Syndrome Therapy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Dravet Syndrome (DS) is a developmental and epileptic encephalopathy predominantly caused by heterozygous loss‐of‐function variants in SCN1A, which encodes Nav1.1. Conserved upstream open reading frames (uORFs) in SCN1A were validated to regulate translation in reporter assays, demonstrating the therapeutic viability of increasing Nav1.1 from ...
Aiswarya Saravanan +7 more
wiley +1 more source