Results 111 to 120 of about 772,314 (296)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Modeling the future distribution of Mediterranean Pinus species [PDF]

, 2013
The potential future distribution of four Mediterranean pines was aimed to be modeled supported by EUFORGEN digital area database (distribution maps), ESRI ArcGIS 10 software’s Spatial Analyst module (modeling environment), PAST (calibration of the model
Bede-Fazekas, Ákos
core  

Targeting TNBC: core–shell polycationic polyurea dendrimers with inherent anticancer activity

FEBS Open Bio, EarlyView.
Core–shell polycationic PURE dendrimers were tested in TNBC‐derived tumor models. Both formulations selectively targeted TNBC and effectively reduced tumor volume. PUREG4‐OEI48 suppressed tumor growth without detectable toxicity, whereas PUREG4‐OCEI24, despite showing efficacy, induced hepatic toxicity.
Adriana Cruz, Bruna Abreu, Cindy Mendes, Catarina Freitas‐Dias, Filipe Gonçalves, Fernanda Silva, José Ramalho, Saudade André, Vasco D. B. Bonifácio, Jacinta Serpa   +9 more
wiley   +1 more source

Implications of human induced changes on the distribution of important plant species in the northwestern coastal desert of Egypt

Renewable Energy and Sustainable Development, 2015
The application of species distribution modeling in deserts is a useful tool for mapping species and assessing the impact of human induced changes on individual species.
Marwa Waseem Halmy, Paul E. Gessler, Selim Z. Heneidy   +2 more
doaj   +1 more source

Effect of Electron Energy Distribution Function on Power Deposition and Plasma Density in an Inductively Coupled Discharge at Very Low Pressures

, 2002
A self-consistent 1-D model was developed to study the effect of the electron energy distribution function (EEDF) on power deposition and plasma density profiles in a planar inductively coupled plasma (ICP) in the non-local regime (pressure < 10 mTorr ...
Badri Ramamurthi, Berezhnoi S V, Berezhnoi S V, Blevin H A, Blevin H A, Cohen R H, Demetre J Economou, Demirkhanov R A, Dikman S M, Godyak V A, Godyak V A, Godyak V A, Godyak V A, Hopwood J, Igor D Kaganovich, Kaganovich I D, Kaganovich I D, Kaganovich I D, Kaganovich I D, Keller J H, Kolobov V I, Kolobov V I, Kortshagen U, Liberman M A, Lymberopoulos D P, Paranjpe A P, Piejak R B, Ramamurthi B, Schweigert V A, Shaing K C, Surendra M, Turner M M, Ventzek P L G, Weibel E S, Yoon N S, Yu M Aliev   +35 more
core   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Inferring the similarity of species distributions using Species’ Distribution Models

Ecography, 2013
A common problem in ecology is our need to reliably compare information on the distributions of distinct species. Since it is not always possible to directly compare the distributions of two species, numerous papers now seek to compare the predictions of Species’ Distribution Models (SDMs, estimates of the probability that two species are present ...
openaire   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

SUITABILITY AREAS FOR Candidatus Liberibacter asiaticus UNDER DIFFERENT CLIMATE CHANGE SCENARIOS IN MEXICO

Tropical and Subtropical Agroecosystems
Background. Climate change models have projected an increase in the distribution of certain crop pests of economic importance by forecasting more favorable future conditions for these organisms.
Oliver Rodríguez-Aguilar, Jose López-Collado, Monica de la Cruz Vargas-Mendoza, Alejandra Soto-Estrada, Clemente de Jesus Garcia-Avila   +4 more
doaj   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

FEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc, Blaž Stres, Mirica Karlovits, Igor Karlovits, Petra Jerič, Ondrej Panák, Anja Verbič, Blaž Likozar, Uroš Novak   +8 more
wiley   +1 more source