Results 101 to 110 of about 1,852,936 (285)

TTR.PGM: An R package for modelling the distributions and dynamics of plants using the Thornley transport resistance plant growth model

open access: yesMethods in Ecology and Evolution
An ability to predict the ranges and dynamics of species is central to ecological and evolutionary research. Despite species range modelling being an active area of research for the past three to four decades, methods for predicting species ranges and ...
Steven I. Higgins   +3 more
doaj   +1 more source

Species-free species distribution models describe macroecological properties of protected area networks.

open access: yesPLoS ONE, 2017
Among the greatest challenges facing the conservation of plants and animal species in protected areas are threats from a rapidly changing climate. An altered climate creates both challenges and opportunities for improving the management of protected ...
Jason L Robinson, James A Fordyce
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Integrating Dynamic Subsurface Habitat Metrics Into Species Distribution Models

open access: yesFrontiers in Marine Science, 2018
Species distribution models (SDMs) have become key tools for describing and predicting species habitats. In the marine domain, environmental data used in modeling species distributions are often remotely sensed, and as such have limited capacity for ...
Stephanie Brodie   +17 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova   +25 more
wiley   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Inferring the similarity of species distributions using Species’ Distribution Models

open access: yesEcography, 2013
A common problem in ecology is our need to reliably compare information on the distributions of distinct species. Since it is not always possible to directly compare the distributions of two species, numerous papers now seek to compare the predictions of Species’ Distribution Models (SDMs, estimates of the probability that two species are present ...
openaire   +2 more sources

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

Understanding bio‐based polymers: A study of origins, properties, biodegradation and their impact on health and the environment

open access: yesFEBS Open Bio, EarlyView.
This review provides an overview of bio‐based polymer sources, their unique functional properties and their environmental impact, and addresses their role as sustainable alternatives. It discusses end‐of‐life options, including composting and anaerobic digestion for renewable energy.
Sabina Kolbl Repinc   +8 more
wiley   +1 more source

Tropical rainforest bird community structure in relation to altitude, tree species composition, and null models in the Western Ghats, India

open access: yes, 2005
Studies of species distributions on elevational gradients are essential to understand principles of community organisation as well as to conserve species in montane regions.
Joshi, N. V.   +2 more
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