Results 131 to 140 of about 4,765,745 (329)
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source
The Analysis and Interpretation of Seedling Recruitment Curves [PDF]
, 1993 We derive spatially explicit population models for the interaction between a species of annual plant and a community of perennial species. The models are used to explore the conditions for persistence of the annual in both a constant and a stochastic ...
Rees, M., Long, M.J.
core +1 more source
Scaling Limits for Multispecies Statistical Mechanics Mean-Field Models
, 2011 We study the limiting thermodynamic behavior of the normalized sums of spins in multi-species Curie-Weiss models. We find sufficient conditions for the limiting random vector to be Gaussian (or to have an exponential distribution of higher order) and ...
Contucci, Pierluigi, Fedele, Micaela
core +1 more source
Journal of Biogeography, 2019 We present a novel strategy for species distribution models (SDMs) aimed at predicting the potential distributions of range‐expanding invasive non‐native species (INNS). The strategy combines two established perspectives on defining the background region
Daniel S. Chapman +3 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns +10 more
wiley +1 more source
Simulating Root Density Dynamics and Nitrogen Uptake – Can a Simple Approach be Sufficient? [PDF]
, 2007 The modeling of root growth in many plant–soil models is simple and with few possibilities to adapt simulated root proliferation and depth distribution to that actually found with different crop species.
Jensen, Lars Stoumann +3 more
core
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano +6 more
wiley +1 more source
Moving Beyond Static Species Distribution Models in Support of Conservation Biogeography [PDF]
Aim: To demonstrate that multi-modeling methods have effectively been used to combine static species distribution models (SDM), predicting the geographical pattern of suitable habitat, with dynamics landscape and population models in order to forecast ...
Janet Franklin
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source