Results 101 to 110 of about 1,342,717 (316)

Evaluating preservation methods for identifying Anopheles gambiae s.s. and Anopheles arabiensis complex mosquitoes species using near infra-red spectroscopy. [PDF]

, 2015
BACKGROUND: Near-infrared spectroscopy (NIRS) has been successfully used on fresh and RNAlater-preserved members of the Anopheles gambiae complex to identify sibling species and age.
Marta Ferreira Maia, Mayagaya, Valeriana, Ntamatungiro, Alex, Sarah Jane Moore, Robert Andrew Wirtz, Maia, Marta Ferreira, Valeriana Simon Mayagaya, Wirtz, Robert Andrew, Alex John Ntamatungiro, Wirtz, Robert, Mayagaya, Valeriana Simon, Dowell, Floyd, Maia, Marta, Dowell, Floyd Ercell, Ntamatungiro, Alex John, Moore, Sarah, Moore, Sarah Jane, Floyd Ercell Dowell   +17 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Defining bacterial species in the genomic era : insights from the genus Acinetobacter [PDF]

, 2012
Background: Microbial taxonomy remains a conservative discipline, relying on phenotypic information derived from growth in pure culture and techniques that are time-consuming and difficult to standardize, particularly when compared to the ease of modern
Loman, Nicholas J, Chan, Jacqueline, Nicholas J Loman, Chan, Jacqueline Z-m, Constantinidou, Chrystala, Loman Nicholas J, Halachev, Mihail R, Pallen, Mark J, Pallen, Mark J., Halachev Mihail R, Mihail R Halachev, Loman, Nicholas J., Pallen Mark J, Halachev, Mihail R., Jacqueline Z-M Chan, Chrystala Constantinidou, Chan Jacqueline Z-M, Constantinidou Chrystala, Mark J Pallen   +18 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Comparative chloroplast genome and species discrimination analyses in Aralia section Aralia (Araliaceae)

Journal of Asia-Pacific Biodiversity
Aralia section Aralia is a subset of Araliaceae; it constitutes a small lineage that has been utilized in East Asian traditional medicines for centuries.
Menghao Wang, Xinru Ma, Mengyi Yang, Tengfei Wang, Zhuang Xing, Yanyan Liu, Jingli Yan, Jiamei Li, Yanan Cao   +8 more
doaj   +1 more source

The complete mitochondrial genome of Chrysomya nigripes (Diptera: Calliphoridae)

Mitochondrial DNA. Part B. Resources, 2019
Chrysomya nigripes (Diptera: Calliphoridae) is a blow fly species of forensic importance. Here we demonstrated the complete mitochondrial genome of this species for the first time.
Ze-Ya Zhang, Li-Pin Ren, Jing Leng, Yan-Jie Shang, Guang-Hui Zhu   +4 more
doaj   +1 more source

Using molecular tools to differentiate closely related blackfly species of the genus Simulium

, 2008
Biodiversity data are the foundation for conservation and managemet and taxonomy provides the reference system, skills and tools used to identify organisms.
Day, J.C., Day, J. C.
core  

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Origins of the amphiploid species Brassica napus L. investigated by chloroplast and nuclear molecular markers [PDF]

, 2010
Background: The amphiploid species Brassica napus (oilseed rape, Canola) is a globally important oil crop yielding food, biofuels and industrial compounds such as lubricants and surfactants.
Allender, Charlotte J, Allender, Charlotte J., King, Graham J, King , Graham J., King Graham J, King, G. J., Charlotte J Allender, Graham J King, Allender Charlotte J, Allender, C. J.   +9 more
core   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source